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Renal transporters in drug development.
Morrissey KM, Stocker SL, Wittwer MB, Xu L, Giacomini KM. Morrissey KM, et al. Among authors: xu l. Annu Rev Pharmacol Toxicol. 2013;53:503-29. doi: 10.1146/annurev-pharmtox-011112-140317. Epub 2012 Nov 8. Annu Rev Pharmacol Toxicol. 2013. PMID: 23140242 Review.
OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin.
Chen L, Shu Y, Liang X, Chen EC, Yee SW, Zur AA, Li S, Xu L, Keshari KR, Lin MJ, Chien HC, Zhang Y, Morrissey KM, Liu J, Ostrem J, Younger NS, Kurhanewicz J, Shokat KM, Ashrafi K, Giacomini KM. Chen L, et al. Among authors: xu l. Proc Natl Acad Sci U S A. 2014 Jul 8;111(27):9983-8. doi: 10.1073/pnas.1314939111. Epub 2014 Jun 24. Proc Natl Acad Sci U S A. 2014. PMID: 24961373 Free PMC article.
Genetic and epigenetic regulation of the organic cation transporter 3, SLC22A3.
Chen L, Hong C, Chen EC, Yee SW, Xu L, Almof EU, Wen C, Fujii K, Johns SJ, Stryke D, Ferrin TE, Simko J, Chen X, Costello JF, Giacomini KM. Chen L, et al. Among authors: xu l. Pharmacogenomics J. 2013 Apr;13(2):110-20. doi: 10.1038/tpj.2011.60. Epub 2012 Jan 10. Pharmacogenomics J. 2013. PMID: 22231567 Free PMC article.
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