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Myeloid deletion of SIRT1 induces inflammatory signaling in response to environmental stress.
Schug TT, Xu Q, Gao H, Peres-da-Silva A, Draper DW, Fessler MB, Purushotham A, Li X. Schug TT, et al. Mol Cell Biol. 2010 Oct;30(19):4712-21. doi: 10.1128/MCB.00657-10. Epub 2010 Jul 20. Mol Cell Biol. 2010. PMID: 20647536 Free PMC article.
Triglyceride with medium-chain fatty acids increases the activity and expression of hormone-sensitive lipase in white adipose tissue of C57BL/6J mice.
Liu Y, Xue C, Zhang Y, Xu Q, Yu X, Zhang X, Wang J, Zhang R, Gong X, Guo C. Liu Y, et al. Biosci Biotechnol Biochem. 2011;75(10):1939-44. doi: 10.1271/bbb.110321. Epub 2011 Oct 7. Biosci Biotechnol Biochem. 2011. PMID: 21979067
Hepatic deletion of SIRT1 decreases hepatocyte nuclear factor 1α/farnesoid X receptor signaling and induces formation of cholesterol gallstones in mice.
Purushotham A, Xu Q, Lu J, Foley JF, Yan X, Kim DH, Kemper JK, Li X. Purushotham A, et al. Mol Cell Biol. 2012 Apr;32(7):1226-36. doi: 10.1128/MCB.05988-11. Epub 2012 Jan 30. Mol Cell Biol. 2012. PMID: 22290433 Free PMC article.
Intestinal Epithelial Sirtuin 1 Regulates Intestinal Inflammation During Aging in Mice by Altering the Intestinal Microbiota.
Wellman AS, Metukuri MR, Kazgan N, Xu X, Xu Q, Ren NSX, Czopik A, Shanahan MT, Kang A, Chen W, Azcarate-Peril MA, Gulati AS, Fargo DC, Guarente L, Li X. Wellman AS, et al. Gastroenterology. 2017 Sep;153(3):772-786. doi: 10.1053/j.gastro.2017.05.022. Epub 2017 May 26. Gastroenterology. 2017. PMID: 28552621 Free PMC article.
Methionine metabolism is essential for SIRT1-regulated mouse embryonic stem cell maintenance and embryonic development.
Tang S, Fang Y, Huang G, Xu X, Padilla-Banks E, Fan W, Xu Q, Sanderson SM, Foley JF, Dowdy S, McBurney MW, Fargo DC, Williams CJ, Locasale JW, Guan Z, Li X. Tang S, et al. EMBO J. 2017 Nov 2;36(21):3175-3193. doi: 10.15252/embj.201796708. Epub 2017 Oct 11. EMBO J. 2017. PMID: 29021282 Free PMC article.
HNF4α regulates sulfur amino acid metabolism and confers sensitivity to methionine restriction in liver cancer.
Xu Q, Li Y, Gao X, Kang K, Williams JG, Tong L, Liu J, Ji M, Deterding LJ, Tong X, Locasale JW, Li L, Shats I, Li X. Xu Q, et al. Nat Commun. 2020 Aug 7;11(1):3978. doi: 10.1038/s41467-020-17818-w. Nat Commun. 2020. PMID: 32770044 Free PMC article.
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