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Cancer proliferation gene discovery through functional genomics.
Schlabach MR, Luo J, Solimini NL, Hu G, Xu Q, Li MZ, Zhao Z, Smogorzewska A, Sowa ME, Ang XL, Westbrook TF, Liang AC, Chang K, Hackett JA, Harper JW, Hannon GJ, Elledge SJ. Schlabach MR, et al. Among authors: xu q. Science. 2008 Feb 1;319(5863):620-4. doi: 10.1126/science.1149200. Science. 2008. PMID: 18239126 Free PMC article.
Design of 240,000 orthogonal 25mer DNA barcode probes.
Xu Q, Schlabach MR, Hannon GJ, Elledge SJ. Xu Q, et al. Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2289-94. doi: 10.1073/pnas.0812506106. Epub 2009 Jan 26. Proc Natl Acad Sci U S A. 2009. PMID: 19171886 Free PMC article.
Global identification of modular cullin-RING ligase substrates.
Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ. Emanuele MJ, et al. Among authors: xu q. Cell. 2011 Oct 14;147(2):459-74. doi: 10.1016/j.cell.2011.09.019. Epub 2011 Sep 29. Cell. 2011. PMID: 21963094 Free PMC article.
A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis.
Kessler JD, Kahle KT, Sun T, Meerbrey KL, Schlabach MR, Schmitt EM, Skinner SO, Xu Q, Li MZ, Hartman ZC, Rao M, Yu P, Dominguez-Vidana R, Liang AC, Solimini NL, Bernardi RJ, Yu B, Hsu T, Golding I, Luo J, Osborne CK, Creighton CJ, Hilsenbeck SG, Schiff R, Shaw CA, Elledge SJ, Westbrook TF. Kessler JD, et al. Among authors: xu q. Science. 2012 Jan 20;335(6066):348-53. doi: 10.1126/science.1212728. Epub 2011 Dec 8. Science. 2012. PMID: 22157079 Free PMC article.
Recurrent hemizygous deletions in cancers may optimize proliferative potential.
Solimini NL, Xu Q, Mermel CH, Liang AC, Schlabach MR, Luo J, Burrows AE, Anselmo AN, Bredemeyer AL, Li MZ, Beroukhim R, Meyerson M, Elledge SJ. Solimini NL, et al. Among authors: xu q. Science. 2012 Jul 6;337(6090):104-9. doi: 10.1126/science.1219580. Epub 2012 May 24. Science. 2012. PMID: 22628553 Free PMC article.
STOP gene Phactr4 is a tumor suppressor.
Solimini NL, Liang AC, Xu C, Pavlova NN, Xu Q, Davoli T, Li MZ, Wong KK, Elledge SJ. Solimini NL, et al. Among authors: xu q, xu c. Proc Natl Acad Sci U S A. 2013 Jan 29;110(5):E407-14. doi: 10.1073/pnas.1221385110. Epub 2013 Jan 14. Proc Natl Acad Sci U S A. 2013. PMID: 23319639 Free PMC article.
18,399 results
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