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SETD2 regulates the maternal epigenome, genomic imprinting and embryonic development.
Xu Q, Xiang Y, Wang Q, Wang L, Brind'Amour J, Bogutz AB, Zhang Y, Zhang B, Yu G, Xia W, Du Z, Huang C, Ma J, Zheng H, Li Y, Liu C, Walker CL, Jonasch E, Lefebvre L, Wu M, Lorincz MC, Li W, Li L, Xie W. Xu Q, et al. Nat Genet. 2019 May;51(5):844-856. doi: 10.1038/s41588-019-0398-7. Epub 2019 Apr 29. Nat Genet. 2019. PMID: 31040401
Allelic reprogramming of the histone modification H3K4me3 in early mammalian development.
Zhang B, Zheng H, Huang B, Li W, Xiang Y, Peng X, Ming J, Wu X, Zhang Y, Xu Q, Liu W, Kou X, Zhao Y, He W, Li C, Chen B, Li Y, Wang Q, Ma J, Yin Q, Kee K, Meng A, Gao S, Xu F, Na J, Xie W. Zhang B, et al. Among authors: xu q, xu f. Nature. 2016 Sep 22;537(7621):553-557. doi: 10.1038/nature19361. Epub 2016 Sep 14. Nature. 2016. PMID: 27626382
Polycomb Group Proteins Regulate Chromatin Architecture in Mouse Oocytes and Early Embryos.
Du Z, Zheng H, Kawamura YK, Zhang K, Gassler J, Powell S, Xu Q, Lin Z, Xu K, Zhou Q, Ozonov EA, Véron N, Huang B, Li L, Yu G, Liu L, Au Yeung WK, Wang P, Chang L, Wang Q, He A, Sun Y, Na J, Sun Q, Sasaki H, Tachibana K, Peters AHFM, Xie W. Du Z, et al. Among authors: xu k, xu q. Mol Cell. 2020 Feb 20;77(4):825-839.e7. doi: 10.1016/j.molcel.2019.11.011. Epub 2019 Dec 11. Mol Cell. 2020. PMID: 31837995 Free article.
The landscape of RNA Pol II binding reveals a stepwise transition during ZGA.
Liu B, Xu Q, Wang Q, Feng S, Lai F, Wang P, Zheng F, Xiang Y, Wu J, Nie J, Qiu C, Xia W, Li L, Yu G, Lin Z, Xu K, Xiong Z, Kong F, Liu L, Huang C, Yu Y, Na J, Xie W. Liu B, et al. Among authors: xu k, xu q. Nature. 2020 Nov;587(7832):139-144. doi: 10.1038/s41586-020-2847-y. Epub 2020 Oct 28. Nature. 2020. PMID: 33116310
Formative pluripotent stem cells show features of epiblast cells poised for gastrulation.
Wang X, Xiang Y, Yu Y, Wang R, Zhang Y, Xu Q, Sun H, Zhao ZA, Jiang X, Wang X, Lu X, Qin D, Quan Y, Zhang J, Shyh-Chang N, Wang H, Jing N, Xie W, Li L. Wang X, et al. Among authors: xu q. Cell Res. 2021 May;31(5):526-541. doi: 10.1038/s41422-021-00477-x. Epub 2021 Feb 19. Cell Res. 2021. PMID: 33608671 Free PMC article.
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