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Physiologically-Based Pharmacokinetic-Pharmacodynamics Model Characterizing CYP2C19 Polymorphisms to Predict Clopidogrel Pharmacokinetics and Its Anti-Platelet Aggregation Effect Following Oral Administration to Coronary Artery Disease Patients With or Without Diabetes.
Xu RJ, Kong WM, An XF, Zou JJ, Liu L, Liu XD. Xu RJ, et al. Front Pharmacol. 2020 Dec 17;11:593982. doi: 10.3389/fphar.2020.593982. eCollection 2020. Front Pharmacol. 2020. PMID: 33519456 Free PMC article.
Physiologically based pharmacokinetic-pharmacodynamic modeling for prediction of vonoprazan pharmacokinetics and its inhibition on gastric acid secretion following intravenous/oral administration to rats, dogs and humans.
Kong WM, Sun BB, Wang ZJ, Zheng XK, Zhao KJ, Chen Y, Zhang JX, Liu PH, Zhu L, Xu RJ, Li P, Liu L, Liu XD. Kong WM, et al. Among authors: xu rj. Acta Pharmacol Sin. 2020 Jun;41(6):852-865. doi: 10.1038/s41401-019-0353-2. Epub 2020 Jan 22. Acta Pharmacol Sin. 2020. PMID: 31969689 Free PMC article.
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