Xu W - Search Results

1

Asymmetric Hsp90 N domain SUMOylation recruits Aha1 and ATP-competitive inhibitors.

Mollapour M, Bourboulia D, Beebe K, Woodford MR, Polier S, Hoang A, Chelluri R, Li Y, Guo A, Lee MJ, Fotooh-Abadi E, Khan S, Prince T, Miyajima N, Yoshida S, Tsutsumi S, Xu W, Panaretou B, Stetler-Stevenson WG, Bratslavsky G, Trepel JB, Prodromou C, Neckers L. Mollapour M, et al. Among authors: xu w. Mol Cell. 2014 Jan 23;53(2):317-29. doi: 10.1016/j.molcel.2013.12.007. Mol Cell. 2014. PMID: 24462205 Free PMC article.

2

Loss of Hsp90 association up-regulates Src-dependent ErbB2 activity.

Xu W, Yuan X, Beebe K, Xiang Z, Neckers L. Xu W, et al. Mol Cell Biol. 2007 Jan;27(1):220-8. doi: 10.1128/MCB.00899-06. Epub 2006 Oct 9. Mol Cell Biol. 2007. PMID: 17030621 Free PMC article.

3

Cancer cells harboring MET gene amplification activate alternative signaling pathways to escape MET inhibition but remain sensitive to Hsp90 inhibitors.

Wang S, Pashtan I, Tsutsumi S, Xu W, Neckers L. Wang S, et al. Among authors: xu w. Cell Cycle. 2009 Jul 1;8(13):2050-6. doi: 10.4161/cc.8.13.8861. Epub 2009 Jul 27. Cell Cycle. 2009. PMID: 19502802 Free PMC article.

4

Hsp90 charged-linker truncation reverses the functional consequences of weakened hydrophobic contacts in the N domain.

Tsutsumi S, Mollapour M, Graf C, Lee CT, Scroggins BT, Xu W, Haslerova L, Hessling M, Konstantinova AA, Trepel JB, Panaretou B, Buchner J, Mayer MP, Prodromou C, Neckers L. Tsutsumi S, et al. Among authors: xu w. Nat Struct Mol Biol. 2009 Nov;16(11):1141-7. doi: 10.1038/nsmb.1682. Epub 2009 Oct 18. Nat Struct Mol Biol. 2009. PMID: 19838189 Free PMC article.

5

Threonine 22 phosphorylation attenuates Hsp90 interaction with cochaperones and affects its chaperone activity.

Mollapour M, Tsutsumi S, Truman AW, Xu W, Vaughan CK, Beebe K, Konstantinova A, Vourganti S, Panaretou B, Piper PW, Trepel JB, Prodromou C, Pearl LH, Neckers L. Mollapour M, et al. Among authors: xu w. Mol Cell. 2011 Mar 18;41(6):672-81. doi: 10.1016/j.molcel.2011.02.011. Mol Cell. 2011. PMID: 21419342 Free PMC article.

6

Dynamic tyrosine phosphorylation modulates cycling of the HSP90-P50(CDC37)-AHA1 chaperone machine.

Xu W, Mollapour M, Prodromou C, Wang S, Scroggins BT, Palchick Z, Beebe K, Siderius M, Lee MJ, Couvillon A, Trepel JB, Miyata Y, Matts R, Neckers L. Xu W, et al. Mol Cell. 2012 Aug 10;47(3):434-43. doi: 10.1016/j.molcel.2012.05.015. Epub 2012 Jun 21. Mol Cell. 2012. PMID: 22727666 Free PMC article.

7

Gr(i)p the ER to Stress Out Melanoma.

Xu W, Neckers L. Xu W, et al. Cancer Cell. 2016 Jun 13;29(6):769-771. doi: 10.1016/j.ccell.2016.05.006. Cancer Cell. 2016. PMID: 27300428 Free article.

8

Hsp90 middle domain phosphorylation initiates a complex conformational program to recruit the ATPase-stimulating cochaperone Aha1.

Xu W, Beebe K, Chavez JD, Boysen M, Lu Y, Zuehlke AD, Keramisanou D, Trepel JB, Prodromou C, Mayer MP, Bruce JE, Gelis I, Neckers L. Xu W, et al. Nat Commun. 2019 Jun 12;10(1):2574. doi: 10.1038/s41467-019-10463-y. Nat Commun. 2019. PMID: 31189925 Free PMC article.

9

Hsp90, not Grp94, regulates the intracellular trafficking and stability of nascent ErbB2.

Xu W, Mimnaugh EG, Kim JS, Trepel JB, Neckers LM. Xu W, et al. Cell Stress Chaperones. 2002 Jan;7(1):91-6. doi: 10.1379/1466-1268(2002)007<0091:hngrti>2.0.co;2. Cell Stress Chaperones. 2002. PMID: 11892991 Free PMC article.

10

Heat shock protein 90 as a molecular target for cancer therapeutics.

Isaacs JS, Xu W, Neckers L. Isaacs JS, et al. Among authors: xu w. Cancer Cell. 2003 Mar;3(3):213-7. doi: 10.1016/s1535-6108(03)00029-1. Cancer Cell. 2003. PMID: 12676580 Free article. Review. No abstract available.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

27,805 results

Search Page