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Yo jyo hen shi ko, a novel Chinese herbal, prevents nonalcoholic steatohepatitis in ob/ob mice fed a high fat or methionine-choline-deficient diet.
de Lima VM, de Oliveira CP, Sawada LY, Barbeiro HV, de Mello ES, Soriano FG, Alves VA, Caldwell SH, Carrilho FJ. de Lima VM, et al. Liver Int. 2007 Mar;27(2):227-34. doi: 10.1111/j.1478-3231.2006.01405.x. Liver Int. 2007. PMID: 17311618
BACKGROUND: Oxidative stress plays a role in the pathogenesis of nonalcoholic steatohepatitis (NASH). Yo jyo hen shi ko (YHK) is a complex compound purported to reduce reactive oxygen species (ROS) by blocking the propagation of radical-i …
BACKGROUND: Oxidative stress plays a role in the pathogenesis of nonalcoholic steatohepatitis (NASH). Yo jyo hen shi
Yo Jyo Hen Shi Ko (YHK) improves transaminases in nonalcoholic steatohepatitis (NASH): a randomized pilot study.
Chande N, Laidlaw M, Adams P, Marotta P. Chande N, et al. Dig Dis Sci. 2006 Jul;51(7):1183-9. doi: 10.1007/s10620-006-8030-y. Dig Dis Sci. 2006. PMID: 16944007 Clinical Trial.
Eight patients were randomized to YHK or placebo for 8 weeks. The ALT and AST were measured at baseline and weeks 4, 8, and 12. ...YHK is well tolerated. Further studies are justified to assess the impact of YHK in the natural history of NASH....
Eight patients were randomized to YHK or placebo for 8 weeks. The ALT and AST were measured at baseline and weeks 4, 8, and 12. ... …
Nonalcoholic steatohepatitis (NASH) in ob/ob mice treated with yo jyo hen shi ko (YHK): effects on peroxisome proliferator-activated receptors (PPARs) and microsomal triglyceride transfer protein (MTP).
Stefano JT, de Oliveira CP, Corrêa-Giannella ML, de Lima VM, de Sá SV, de Oliveira EP, de Mello ES, Giannella-Neto D, Alves VA, Carrilho FJ. Stefano JT, et al. Dig Dis Sci. 2007 Dec;52(12):3448-54. doi: 10.1007/s10620-007-9810-8. Epub 2007 Mar 30. Dig Dis Sci. 2007. PMID: 17394061
YHK has antioxidant properties, has a hypoglycemic effect, and may reduce plasma lipid levels. In this study, we examined the hepatic expression of PPAR-alpha and -gamma and MTP in ob/ob mice receiving or not receiving YHK. Ob/ob mice were assigned to receive oral
YHK has antioxidant properties, has a hypoglycemic effect, and may reduce plasma lipid levels. In this study, we examined the hepatic
Anti-inflammatory and anti-mutagenic effect of the YHK phytocompound in hepatocytes: in view of an age-management liver-protecting approach.
Catanzaro R, Celep G, Illuzzi N, Milazzo M, Rastmanesh R, Yaduvanshi SK, He F, Trushin M, Sapienza C, Srivastava N, Marotta F. Catanzaro R, et al. Rejuvenation Res. 2014 Apr;17(2):168-71. doi: 10.1089/rej.2013.1492. Epub 2014 Apr 8. Rejuvenation Res. 2014. PMID: 24050307
The receptor for advanced glycation end products (RAGE) regulates cellular proliferation in hepatocellular carcinoma (HCC). The aim of this study was to test the in vitro effect of Yo Jyo Hen Shi Ko (YHK), a nutraceutical with prior data …
The receptor for advanced glycation end products (RAGE) regulates cellular proliferation in hepatocellular carcinoma (HCC). The aim of this …
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