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Equine metabolism of the selective androgen receptor modulator YK-11 in urine and plasma following oral administration.
Harding C, Viljanto M, Habershon-Butcher J, Taylor P, Scarth J. Harding C, et al. Drug Test Anal. 2023 Apr;15(4):388-407. doi: 10.1002/dta.3425. Epub 2023 Jan 4. Drug Test Anal. 2023. PMID: 36519889
YK-11 is a steroidal selective androgen receptor modulator, a compound class prohibited in both equine racing and human sports because of their potentially performance enhancing properties. ...The purpose of this study was to investigate the in vivo me
YK-11 is a steroidal selective androgen receptor modulator, a compound class prohibited in both equine racing an
Mass spectrometric characterization of the selective androgen receptor modulator (SARM) YK-11 for doping control purposes.
Thevis M, Piper T, Dib J, Lagojda A, Kühne D, Packschies L, Geyer H, Schänzer W. Thevis M, et al. Rapid Commun Mass Spectrom. 2017 Jul 30;31(14):1175-1183. doi: 10.1002/rcm.7886. Rapid Commun Mass Spectrom. 2017. PMID: 28440570
RATIONALE: Selective androgen receptor modulators (SARMs) represent an emerging class of therapeutics targeting inter alia conditions referred to as cachexia and sarcopenia. ...Hence, in the present study the mass spectrometric properties of the SARM YK-11
RATIONALE: Selective androgen receptor modulators (SARMs) represent an emerging class of therapeutics targeting inter alia con …
Detection of SARMs in doping control analysis.
Thevis M, Schänzer W. Thevis M, et al. Mol Cell Endocrinol. 2018 Mar 15;464:34-45. doi: 10.1016/j.mce.2017.01.040. Epub 2017 Jan 27. Mol Cell Endocrinol. 2018. PMID: 28137616 Review.
The class of selective androgen receptor modulators (SARMs) has been the subject of intense and dedicated clinical research over the past two decades. ...Doping control analytical approaches predominantly rely on chromatography hyphenated to mass spectrometry, which …
The class of selective androgen receptor modulators (SARMs) has been the subject of intense and dedicated clinical research ov …
Detection of nonsteroidal and steroidal selective androgen receptor modulators in equine hair after oral administrations.
So YM, Kong FK, Kwok WH, Kwok KY, Wan TSM, Ho EN. So YM, et al. Drug Test Anal. 2025 May;17(5):655-662. doi: 10.1002/dta.3772. Epub 2024 Jul 12. Drug Test Anal. 2025. PMID: 39001560
This paper describes the detections of nonsteroidal and steroidal selective androgen receptor modulators (SARMs), namely, RAD140 and YK-11, in mane hair collected from horses having been orally administered with the respective drugs. SARMs are potent a …
This paper describes the detections of nonsteroidal and steroidal selective androgen receptor modulators (SARMs), namely, RAD1 …
Development and validation of liquid chromatography-tandem mass spectrometry method for screening six selective androgen receptor modulators in dietary supplements.
Lee JH, Han JH, Jung EJ, Nallapaneni HK, Kim NS, Kim H, Lee J, Baek SY. Lee JH, et al. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2021 Jul;38(7):1075-1086. doi: 10.1080/19440049.2021.1906954. Epub 2021 May 1. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2021. PMID: 33934684
Selective androgen receptor modulators (SARMs) are compounds with specific androgenic properties that have been investigated for the treatment of conditions such as muscle wasting disease. ...Although YK-11 is particularly unstable, such that the proto …
Selective androgen receptor modulators (SARMs) are compounds with specific androgenic properties that have been investigated f …