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Ternatin, a cyclic peptide isolated from mushroom, and its derivative suppress hyperglycemia and hepatic fatty acid synthesis in spontaneously diabetic KK-A(y) mice.
Kobayashi M, Kawashima H, Takemori K, Ito H, Murai A, Masuda S, Yamada K, Uemura D, Horio F. Kobayashi M, et al. Among authors: yamada k. Biochem Biophys Res Commun. 2012 Oct 19;427(2):299-304. doi: 10.1016/j.bbrc.2012.09.045. Epub 2012 Sep 18. Biochem Biophys Res Commun. 2012. PMID: 23000156
(-)-Ternatin inhibits adipogenesis and lipid metabolism in 3T3-L1 cells.
Ito M, Ito J, Kitazawa H, Shimamura K, Fukami T, Tokita S, Shimokawa K, Yamada K, Kanatani A, Uemura D. Ito M, et al. Among authors: yamada k. Peptides. 2009 Jun;30(6):1074-81. doi: 10.1016/j.peptides.2009.02.008. Epub 2009 Feb 21. Peptides. 2009. PMID: 19463739
Convergent synthesis and in vivo inhibitory effect on fat accumulation of (-)-ternatin, a highly N-methylated cyclic peptide.
Shimokawa K, Yamada K, Kita M, Uemura D. Shimokawa K, et al. Among authors: yamada k. Bioorg Med Chem Lett. 2007 Aug 15;17(16):4447-9. doi: 10.1016/j.bmcl.2007.06.015. Epub 2007 Jun 8. Bioorg Med Chem Lett. 2007. PMID: 17590333
(-)-Ternatin (1), a highly N-methylated cyclic heptapeptide, is a potent inhibitor of fat accumulation against 3T3-L1 murine adipocytes (EC50 = 0.14 microg/mL) [Shimokawa, K.; Mashima, I.; Asai, A.; Yamada, K.; Kita, M.; Uemura, D. Tetrahedron Lett. 2006, 47, …
(-)-Ternatin (1), a highly N-methylated cyclic heptapeptide, is a potent inhibitor of fat accumulation against 3T3-L1 murine adipocytes (EC5 …
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