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A new communication system between hepatocytes and sinusoidal endothelial cells in liver through vascular endothelial growth factor and Flt tyrosine kinase receptor family (Flt-1 and KDR/Flk-1).
Yamane A, Seetharam L, Yamaguchi S, Gotoh N, Takahashi T, Neufeld G, Shibuya M. Yamane A, et al. Among authors: yamaguchi s. Oncogene. 1994 Sep;9(9):2683-90. Oncogene. 1994. PMID: 8058332
Co-amplification of c-myc and c-erbB-2 oncogenes in a poorly differentiated human gastric cancer.
Tsuchiya T, Ueyama Y, Tamaoki N, Yamaguchi S, Shibuya M. Tsuchiya T, et al. Among authors: yamaguchi s. Jpn J Cancer Res. 1989 Oct;80(10):920-3. doi: 10.1111/j.1349-7006.1989.tb01626.x. Jpn J Cancer Res. 1989. PMID: 2575609 Free PMC article.
Stimulation by thyroid-stimulating hormone and Grave's immunoglobulin G of vascular endothelial growth factor mRNA expression in human thyroid follicles in vitro and flt mRNA expression in the rat thyroid in vivo.
Sato K, Yamazaki K, Shizume K, Kanaji Y, Obara T, Ohsumi K, Demura H, Yamaguchi S, Shibuya M. Sato K, et al. Among authors: yamaguchi s. J Clin Invest. 1995 Sep;96(3):1295-302. doi: 10.1172/JCI118164. J Clin Invest. 1995. PMID: 7657804 Free PMC article.
[Subtraction cloning of growth arrest inducible genes in normal human epithelial cells].
Yamaguchi S. Yamaguchi S. Kokubyo Gakkai Zasshi. 1995 Mar;62(1):78-93. doi: 10.5357/koubyou.62.78. Kokubyo Gakkai Zasshi. 1995. PMID: 7751801 Japanese.
A unique signal transduction from FLT tyrosine kinase, a receptor for vascular endothelial growth factor VEGF.
Seetharam L, Gotoh N, Maru Y, Neufeld G, Yamaguchi S, Shibuya M. Seetharam L, et al. Among authors: yamaguchi s. Oncogene. 1995 Jan 5;10(1):135-47. Oncogene. 1995. PMID: 7824266
Establishment of a human small cell lung carcinoma cell line carrying amplification of c-myc gene and chromosomal translocation of t(3p;6p) and t(12q;17p).
Kato A, Kamiyama T, Yamaguchi S, Sudo K, Mori S, Sekiguchi M, Aoki N, Shibuya M. Kato A, et al. Among authors: yamaguchi s. Jpn J Cancer Res. 1993 Apr;84(4):355-9. doi: 10.1111/j.1349-7006.1993.tb00143.x. Jpn J Cancer Res. 1993. PMID: 8390424 Free PMC article.
These results suggest that activation of c-myc gene and alteration of gene(s) around these chromosomal breakpoints may play a role in tumorigenesis of GK-T3 SCLC....
These results suggest that activation of c-myc gene and alteration of gene(s) around these chromosomal breakpoints may play a role in …
Flt-1 but not KDR/Flk-1 tyrosine kinase is a receptor for placenta growth factor, which is related to vascular endothelial growth factor.
Sawano A, Takahashi T, Yamaguchi S, Aonuma M, Shibuya M. Sawano A, et al. Among authors: yamaguchi s. Cell Growth Differ. 1996 Feb;7(2):213-21. Cell Growth Differ. 1996. PMID: 8822205
Possible involvement of VEGF-FLT tyrosine kinase receptor system in normal and tumor angiogenesis.
Shibuya M, Seetharam L, Ishii Y, Sawano A, Gotoh N, Matsushime H, Yamaguchi S. Shibuya M, et al. Among authors: yamaguchi s. Princess Takamatsu Symp. 1994;24:162-70. Princess Takamatsu Symp. 1994. PMID: 8983073 Review.
The phosphorylated 1169-tyrosine containing region of flt-1 kinase (VEGFR-1) is a major binding site for PLCgamma.
Sawano A, Takahashi T, Yamaguchi S, Shibuya M. Sawano A, et al. Among authors: yamaguchi s. Biochem Biophys Res Commun. 1997 Sep 18;238(2):487-91. doi: 10.1006/bbrc.1997.7327. Biochem Biophys Res Commun. 1997. PMID: 9299537
Characterization of the extracellular domain in vascular endothelial growth factor receptor-1 (Flt-1 tyrosine kinase).
Tanaka K, Yamaguchi S, Sawano A, Shibuya M. Tanaka K, et al. Among authors: yamaguchi s. Jpn J Cancer Res. 1997 Sep;88(9):867-76. doi: 10.1111/j.1349-7006.1997.tb00463.x. Jpn J Cancer Res. 1997. PMID: 9369935 Free PMC article.
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