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Fluvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl-CoA reductase, scavenges free radicals and inhibits lipid peroxidation in rat liver microsomes.
Yamamoto A, Hoshi K, Ichihara K. Yamamoto A, et al. Eur J Pharmacol. 1998 Nov 13;361(1):143-9. doi: 10.1016/s0014-2999(98)00692-x. Eur J Pharmacol. 1998. PMID: 9851551
We investigated the effect of fluvastatin sodium (fluvastatin) and pravastatin, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, on the formation of thiobarbituric acid reactive substances both in vivo and in vitro in rat liver microsomes and on active oxygen sp …
We investigated the effect of fluvastatin sodium (fluvastatin) and pravastatin, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhib …
Involvement of peripheral mu opioid receptors in scratching behavior in mice.
Yamamoto A, Sugimoto Y. Yamamoto A, et al. Eur J Pharmacol. 2010 Dec 15;649(1-3):336-41. doi: 10.1016/j.ejphar.2010.07.039. Epub 2010 Sep 20. Eur J Pharmacol. 2010. PMID: 20863827
Pruritus is a common adverse effect of opioid treatment. However, the mechanism by which pruritus is induced by opioid administration is unclear. ...These findings suggest that mu opioid receptors play a primary role in peripheral pruritus and that naloxone methiodi …
Pruritus is a common adverse effect of opioid treatment. However, the mechanism by which pruritus is induced by opioid administration …
Characterization of scratching behavior induced by intradermal administration of morphine and fentanyl in mice.
Yamamoto A, Kuyama S, Kamei C, Sugimoto Y. Yamamoto A, et al. Eur J Pharmacol. 2010 Feb 10;627(1-3):162-6. doi: 10.1016/j.ejphar.2009.10.066. Epub 2009 Nov 6. Eur J Pharmacol. 2010. PMID: 19900440
Itching is known as a commonly side effect of opioid administration. However, the relationship of opioid receptors to itching is unclear. ...In addition, an opioid receptor antagonist, naloxone, and a peripherally restricted opioid receptor antagonist, naloxone meth …
Itching is known as a commonly side effect of opioid administration. However, the relationship of opioid receptors to itching is uncl …
Perfluorodecanoic acid enhances the formation of oleic acid in rat liver.
Yamamoto A, Kawashima Y. Yamamoto A, et al. Biochem J. 1997 Jul 15;325 ( Pt 2)(Pt 2):429-34. doi: 10.1042/bj3250429. Biochem J. 1997. PMID: 9230124 Free PMC article.
The feeding of perfluorodecanoic acid (PFDA) to male rats at a dietary concentration of 0.005% (w/w) for 7 days resulted in a marked increase in the activity of microsomal stearoyl-CoA desaturation in the liver. ...A highly significant linear correlation exis …
The feeding of perfluorodecanoic acid (PFDA) to male rats at a dietary concentration of 0.005% (w/w) for 7 days resulted in a
Inhibition of cholesterol synthesis ex vivo and in vivo by fluvastatin, a new inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase.
Yamamoto A, Itoh S, Hoshi K, Ichihara K. Yamamoto A, et al. Experientia. 1995 Mar 15;51(3):223-6. doi: 10.1007/BF01931101. Experientia. 1995. PMID: 7698284
The inhibitory effect of fluvastatin sodium (fluvastatin), a new type of 3-hydroxy-3-methylglutaryl (HMG) coenzyme A inhibitor, on de novo cholesterol synthesis was investigated and compared with that of pravastatin. Fluvastatin at a concentration of 12.5 mg/ …
The inhibitory effect of fluvastatin sodium (fluvastatin), a new type of 3-hydroxy-3-methylglutaryl (HMG) coenzyme A inhibitor …
Studies of repeated administration of FK-506 on myocardial metabolism in rats.
Yoshida A, Yamamoto A, Satoh K, Ichihara K, Hoshi K. Yoshida A, et al. J Toxicol Sci. 1998 Dec;23(5):403-9. doi: 10.2131/jts.23.5_403. J Toxicol Sci. 1998. PMID: 9922943
The effect of a 14-day administration of FK-506 at 1 or 3 mg/kg on plasma lipids and myocardial energy and glucose metabolism in rats was investigated. ...
The effect of a 14-day administration of FK-506 at 1 or 3 mg/kg on plasma lipids and myocardial energy and glucose metabolism in rats …
Improvement of impaired glucose tolerance by oral administration of vanadyl sulfate by gavage in streptozotocin-induced diabetic rats.
Tsunajima T, Tatsuki R, Satoh K, Yamamoto A, Hoshi K, Ichihara K. Tsunajima T, et al. Res Commun Mol Pathol Pharmacol. 1997 Nov;98(2):190-200. Res Commun Mol Pathol Pharmacol. 1997. PMID: 9467827
Vanadyl sulfate at a dose of 25, 50, or 75 mg/kg was given orally by gavage for 2 weeks, starting 12 hours after streptozotocin injection. When vanadyl sulfate was given twice a day, half of the one-day-dosage was given in the morning and the remaining half in the e …
Vanadyl sulfate at a dose of 25, 50, or 75 mg/kg was given orally by gavage for 2 weeks, starting 12 hours after streptozotocin injec …
Effects of EXP3174, a non-peptide angiotensin II receptor antagonist, on renal hemodynamics and renal function in dogs.
Tamaki T, Nishiyama A, Yoshida H, He H, Fukui T, Yamamoto A, Aki Y, Kimura S, Iwao H, Miyatake A, et al. Tamaki T, et al. Eur J Pharmacol. 1993 May 12;236(1):15-21. doi: 10.1016/0014-2999(93)90221-3. Eur J Pharmacol. 1993. PMID: 8319740
We examined the effects of intrarenal infusion of EXP3174, a non-peptide angiotensin II receptor antagonist, in order to evaluate the physiological role of endogenous angiotensin II in regulating renal hemodynamics and urine formation and to assess the possibility of a
We examined the effects of intrarenal infusion of EXP3174, a non-peptide angiotensin II receptor antagonist, in order to evaluate the …
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