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9,987 results
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The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta.
Yin MJ, Yamamoto Y, Gaynor RB. Yin MJ, et al. Among authors: yamamoto y. Nature. 1998 Nov 5;396(6706):77-80. doi: 10.1038/23948. Nature. 1998. PMID: 9817203
The IKK NF-kappa B system: a treasure trove for drug development.
Karin M, Yamamoto Y, Wang QM. Karin M, et al. Among authors: yamamoto y. Nat Rev Drug Discov. 2004 Jan;3(1):17-26. doi: 10.1038/nrd1279. Nat Rev Drug Discov. 2004. PMID: 14708018 Review. No abstract available.
IkappaB kinases: key regulators of the NF-kappaB pathway.
Yamamoto Y, Gaynor RB. Yamamoto Y, et al. Trends Biochem Sci. 2004 Feb;29(2):72-9. doi: 10.1016/j.tibs.2003.12.003. Trends Biochem Sci. 2004. PMID: 15102433 Review.
Nuclear role of I kappa B Kinase-gamma/NF-kappa B essential modulator (IKK gamma/NEMO) in NF-kappa B-dependent gene expression.
Verma UN, Yamamoto Y, Prajapati S, Gaynor RB. Verma UN, et al. Among authors: yamamoto y. J Biol Chem. 2004 Jan 30;279(5):3509-15. doi: 10.1074/jbc.M309300200. Epub 2003 Nov 3. J Biol Chem. 2004. PMID: 14597638
Histone H3 phosphorylation by IKK-alpha is critical for cytokine-induced gene expression.
Yamamoto Y, Verma UN, Prajapati S, Kwak YT, Gaynor RB. Yamamoto Y, et al. Nature. 2003 Jun 5;423(6940):655-9. doi: 10.1038/nature01576. Nature. 2003. PMID: 12789342
Protein phosphatase 2Cbeta association with the IkappaB kinase complex is involved in regulating NF-kappaB activity.
Prajapati S, Verma U, Yamamoto Y, Kwak YT, Gaynor RB. Prajapati S, et al. Among authors: yamamoto y. J Biol Chem. 2004 Jan 16;279(3):1739-46. doi: 10.1074/jbc.M306273200. Epub 2003 Oct 29. J Biol Chem. 2004. PMID: 14585847
HTLV-I Tax protein binds to MEKK1 to stimulate IkappaB kinase activity and NF-kappaB activation.
Yin MJ, Christerson LB, Yamamoto Y, Kwak YT, Xu S, Mercurio F, Barbosa M, Cobb MH, Gaynor RB. Yin MJ, et al. Among authors: yamamoto y. Cell. 1998 May 29;93(5):875-84. doi: 10.1016/s0092-8674(00)81447-6. Cell. 1998. PMID: 9630230
Role of the NF-kappaB pathway in the pathogenesis of human disease states.
Yamamoto Y, Gaynor RB. Yamamoto Y, et al. Curr Mol Med. 2001 Jul;1(3):287-96. doi: 10.2174/1566524013363816. Curr Mol Med. 2001. PMID: 11899077 Review.
Regulation of beta-catenin function by the IkappaB kinases.
Lamberti C, Lin KM, Yamamoto Y, Verma U, Verma IM, Byers S, Gaynor RB. Lamberti C, et al. Among authors: yamamoto y. J Biol Chem. 2001 Nov 9;276(45):42276-86. doi: 10.1074/jbc.M104227200. Epub 2001 Aug 29. J Biol Chem. 2001. PMID: 11527961
IKKgamma /NEMO facilitates the recruitment of the IkappaB proteins into the IkappaB kinase complex.
Yamamoto Y, Kim DW, Kwak YT, Prajapati S, Verma U, Gaynor RB. Yamamoto Y, et al. J Biol Chem. 2001 Sep 28;276(39):36327-36. doi: 10.1074/jbc.M104090200. Epub 2001 Jul 24. J Biol Chem. 2001. PMID: 11470788
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