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The S100A8/A9 heterodimer amplifies proinflammatory cytokine production by macrophages via activation of nuclear factor kappa B and p38 mitogen-activated protein kinase in rheumatoid arthritis.
Sunahori K, Yamamura M, Yamana J, Takasugi K, Kawashima M, Yamamoto H, Chazin WJ, Nakatani Y, Yui S, Makino H. Sunahori K, et al. Among authors: yamamura m. Arthritis Res Ther. 2006;8(3):R69. doi: 10.1186/ar1939. Epub 2006 Apr 13. Arthritis Res Ther. 2006. PMID: 16613612 Free PMC article.
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