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Pelizaeus-Merzbacher disease: cellular pathogenesis and pharmacologic therapy.
Torii T, Miyamoto Y, Yamauchi J, Tanoue A. Torii T, et al. Pediatr Int. 2014 Oct;56(5):659-66. doi: 10.1111/ped.12450. Pediatr Int. 2014. PMID: 25040584 Review.
Protective effect of geranylgeranylacetone via enhancement of HSPB8 induction in desmin-related cardiomyopathy.
Sanbe A, Daicho T, Mizutani R, Endo T, Miyauchi N, Yamauchi J, Tanonaka K, Glabe C, Tanoue A. Sanbe A, et al. PLoS One. 2009;4(4):e5351. doi: 10.1371/journal.pone.0005351. Epub 2009 Apr 28. PLoS One. 2009. PMID: 19399179 Free PMC article.
Cellular signaling of Dock family proteins in neural function.
Miyamoto Y, Yamauchi J. Miyamoto Y, et al. Cell Signal. 2010 Feb;22(2):175-82. doi: 10.1016/j.cellsig.2009.09.036. Epub 2009 Sep 30. Cell Signal. 2010. PMID: 19796679 Review.
The mood stabilizer valproic acid improves defective neurite formation caused by Charcot-Marie-Tooth disease-associated mutant Rab7 through the JNK signaling pathway.
Yamauchi J, Torii T, Kusakawa S, Sanbe A, Nakamura K, Takashima S, Hamasaki H, Kawaguchi S, Miyamoto Y, Tanoue A. Yamauchi J, et al. J Neurosci Res. 2010 Nov 1;88(14):3189-97. doi: 10.1002/jnr.22460. J Neurosci Res. 2010. PMID: 20645406
The atypical Guanine-nucleotide exchange factor, dock7, negatively regulates schwann cell differentiation and myelination.
Yamauchi J, Miyamoto Y, Hamasaki H, Sanbe A, Kusakawa S, Nakamura A, Tsumura H, Maeda M, Nemoto N, Kawahara K, Torii T, Tanoue A. Yamauchi J, et al. J Neurosci. 2011 Aug 31;31(35):12579-92. doi: 10.1523/JNEUROSCI.2738-11.2011. J Neurosci. 2011. PMID: 21880919 Free PMC article.
We previously cloned the dock7 gene encoding the atypical Rho family guanine-nucleotide exchange factor (GEF) and reported the positive role of Dock7, the target Rho GTPases Rac/Cdc42, and the downstream c-Jun N-terminal kinase in Schwann cell migration (Yamauchi et al., 2 …
We previously cloned the dock7 gene encoding the atypical Rho family guanine-nucleotide exchange factor (GEF) and reported the positive role …
Pelizaeus-Merzbacher disease-associated proteolipid protein 1 inhibits oligodendrocyte precursor cell differentiation via extracellular-signal regulated kinase signaling.
Miyamoto Y, Torii T, Tanoue A, Yamauchi J. Miyamoto Y, et al. Biochem Biophys Res Commun. 2012 Jul 27;424(2):262-8. doi: 10.1016/j.bbrc.2012.06.101. Epub 2012 Jun 27. Biochem Biophys Res Commun. 2012. PMID: 22750001
Hypomyelinating leukodystrophy-associated missense mutant of FAM126A/hyccin/DRCTNNB1A aggregates in the endoplasmic reticulum.
Miyamoto Y, Torii T, Eguchi T, Nakamura K, Tanoue A, Yamauchi J. Miyamoto Y, et al. J Clin Neurosci. 2014 Jun;21(6):1033-9. doi: 10.1016/j.jocn.2013.09.014. Epub 2013 Nov 14. J Clin Neurosci. 2014. PMID: 24417797
Hypomyelinating leukodystrophy-associated missense mutation in HSPD1 blunts mitochondrial dynamics.
Miyamoto Y, Eguchi T, Kawahara K, Hasegawa N, Nakamura K, Funakoshi-Tago M, Tanoue A, Tamura H, Yamauchi J. Miyamoto Y, et al. Biochem Biophys Res Commun. 2015 Jul 3;462(3):275-81. doi: 10.1016/j.bbrc.2015.04.132. Epub 2015 May 6. Biochem Biophys Res Commun. 2015. PMID: 25957474
Differentiation of oligodendrocyte progenitor cells from dissociated monolayer and feeder-free cultured pluripotent stem cells.
Yamashita T, Miyamoto Y, Bando Y, Ono T, Kobayashi S, Doi A, Araki T, Kato Y, Shirakawa T, Suzuki Y, Yamauchi J, Yoshida S, Sato N. Yamashita T, et al. PLoS One. 2017 Feb 13;12(2):e0171947. doi: 10.1371/journal.pone.0171947. eCollection 2017. PLoS One. 2017. PMID: 28192470 Free PMC article.
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