Yamazaki H - Search Results

1

Activation and inactivation of carcinogenic dihaloalkanes and other compounds by glutathione S-transferase 5-5 in Salmonella typhimurium tester strain NM5004.

Shimada T, Yamazaki H, Oda Y, Hiratsuka A, Watabe T, Guengerich FP. Shimada T, et al. Among authors: yamazaki h. Chem Res Toxicol. 1996 Jan-Feb;9(1):333-40. doi: 10.1021/tx950125v. Chem Res Toxicol. 1996. PMID: 8924613

2

Activation of trans-1,2-dihydro-1,2-dihydroxy-6-aminochrysene to genotoxic metabolites by rat and human cytochromes P450.

Yamazaki H, Mimura M, Oda Y, Gonzalez FJ, el-Bayoumy K, Chae YH, Guengerich FP, Shimada T. Yamazaki H, et al. Carcinogenesis. 1994 Mar;15(3):465-70. doi: 10.1093/carcin/15.3.465. Carcinogenesis. 1994. PMID: 8118930

3

Roles of different forms of cytochrome P450 in the activation of the promutagen 6-aminochrysene to genotoxic metabolites in human liver microsomes.

Yamazaki H, Mimura M, Oda Y, Inui Y, Shiraga T, Iwasaki K, Guengerich FP, Shimada T. Yamazaki H, et al. Carcinogenesis. 1993 Jul;14(7):1271-8. doi: 10.1093/carcin/14.7.1271. Carcinogenesis. 1993. PMID: 8330339

We reported previously that the potent mutagen 6-aminochrysene is catalyzed principally by rat liver microsomal P4501A and P4502B enzymes to reactive metabolites that induce umu gene expression in O-acetyltransferase-over-expressing strain Salmonella typhimurium NM2009; the propo …

We reported previously that the potent mutagen 6-aminochrysene is catalyzed principally by rat liver microsomal P4501A and P4502B enzymes to …

4

A new Salmonella typhimurium NM5004 strain expressing rat glutathione S-transferase 5-5: use in detection of genotoxicity of dihaloalkanes using an SOS/umu test system.

Oda Y, Yamazaki H, Thier R, Ketterer B, Guengerich FP, Shimada T. Oda Y, et al. Among authors: yamazaki h. Carcinogenesis. 1996 Feb;17(2):297-302. doi: 10.1093/carcin/17.2.297. Carcinogenesis. 1996. PMID: 8625454

5

Aflatoxin B1 8,9-epoxide hydrolysis in the presence of rat and human epoxide hydrolase.

Johnson WW, Yamazaki H, Shimada T, Ueng YF, Guengerich FP. Johnson WW, et al. Among authors: yamazaki h. Chem Res Toxicol. 1997 Jun;10(6):672-6. doi: 10.1021/tx960209j. Chem Res Toxicol. 1997. PMID: 9208174

6

Inhibition of human cytochrome P450-catalyzed oxidations of xenobiotics and procarcinogens by synthetic organoselenium compounds.

Shimada T, El-Bayoumy K, Upadhyaya P, Sutter TR, Guengerich FP, Yamazaki H. Shimada T, et al. Among authors: yamazaki h. Cancer Res. 1997 Nov 1;57(21):4757-64. Cancer Res. 1997. PMID: 9354437

7

Roles of cytochromes P450 1A2 and 3A4 in the oxidation of estradiol and estrone in human liver microsomes.

Yamazaki H, Shaw PM, Guengerich FP, Shimada T. Yamazaki H, et al. Chem Res Toxicol. 1998 Jun;11(6):659-65. doi: 10.1021/tx970217f. Chem Res Toxicol. 1998. PMID: 9625734

8

Selectivity of polycyclic inhibitors for human cytochrome P450s 1A1, 1A2, and 1B1.

Shimada T, Yamazaki H, Foroozesh M, Hopkins NE, Alworth WL, Guengerich FP. Shimada T, et al. Among authors: yamazaki h. Chem Res Toxicol. 1998 Sep;11(9):1048-56. doi: 10.1021/tx980090+. Chem Res Toxicol. 1998. PMID: 9760279

9

Role of human N-acetyltransferases, NAT1 or NAT2, in genotoxicity of nitroarenes and aromatic amines in Salmonella typhimurium NM6001 and NM6002.

Oda Y, Yamazaki H, Shimada T. Oda Y, et al. Among authors: yamazaki h. Carcinogenesis. 1999 Jun;20(6):1079-83. doi: 10.1093/carcin/20.6.1079. Carcinogenesis. 1999. PMID: 10357791

10

Rat pulmonary microsomal cytochrome P-450 enzymes involved in the activation of procarcinogens.

Shimada T, Yamazaki H, Mimura M, Guengerich FP. Shimada T, et al. Among authors: yamazaki h. Mutat Res. 1992 Dec 16;284(2):233-41. doi: 10.1016/0027-5107(92)90007-o. Mutat Res. 1992. PMID: 1281274

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