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Identification of isothiazole-4-carboxamidines derivatives as a novel class of allosteric MEK1 inhibitors.
El Abdellaoui H, Varaprasad CV, Barawkar D, Chakravarty S, Maderna A, Tam R, Chen H, Allan M, Wu JZ, Appleby T, Yan S, Zhang W, Lang S, Yao N, Hamatake R, Hong Z. El Abdellaoui H, et al. Among authors: yan s. Bioorg Med Chem Lett. 2006 Nov 1;16(21):5561-6. doi: 10.1016/j.bmcl.2006.08.048. Epub 2006 Aug 24. Bioorg Med Chem Lett. 2006. PMID: 16934458
Identification of novel, selective and potent Chk2 inhibitors.
Larson G, Yan S, Chen H, Rong F, Hong Z, Wu JZ. Larson G, et al. Among authors: yan s. Bioorg Med Chem Lett. 2007 Jan 1;17(1):172-5. doi: 10.1016/j.bmcl.2006.09.067. Epub 2006 Oct 10. Bioorg Med Chem Lett. 2007. PMID: 17035018
Isothiazoles as active-site inhibitors of HCV NS5B polymerase.
Yan S, Appleby T, Gunic E, Shim JH, Tasu T, Kim H, Rong F, Chen H, Hamatake R, Wu JZ, Hong Z, Yao N. Yan S, et al. Bioorg Med Chem Lett. 2007 Jan 1;17(1):28-33. doi: 10.1016/j.bmcl.2006.10.002. Epub 2006 Oct 5. Bioorg Med Chem Lett. 2007. PMID: 17049853
Discovery of the First Potent Inhibitors of Mutant IDH1 That Lower Tumor 2-HG in Vivo.
Popovici-Muller J, Saunders JO, Salituro FG, Travins JM, Yan S, Zhao F, Gross S, Dang L, Yen KE, Yang H, Straley KS, Jin S, Kunii K, Fantin VR, Zhang S, Pan Q, Shi D, Biller SA, Su SM. Popovici-Muller J, et al. Among authors: yan s. ACS Med Chem Lett. 2012 Sep 17;3(10):850-5. doi: 10.1021/ml300225h. eCollection 2012 Oct 11. ACS Med Chem Lett. 2012. PMID: 24900389 Free PMC article.
9,667 results