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DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer.
Mao C, Liu X, Zhang Y, Lei G, Yan Y, Lee H, Koppula P, Wu S, Zhuang L, Fang B, Poyurovsky MV, Olszewski K, Gan B. Mao C, et al. Among authors: yan y. Nature. 2021 May;593(7860):586-590. doi: 10.1038/s41586-021-03539-7. Epub 2021 May 12. Nature. 2021. PMID: 33981038 Free PMC article.
Actin cytoskeleton vulnerability to disulfide stress mediates disulfidptosis.
Liu X, Nie L, Zhang Y, Yan Y, Wang C, Colic M, Olszewski K, Horbath A, Chen X, Lei G, Mao C, Wu S, Zhuang L, Poyurovsky MV, James You M, Hart T, Billadeau DD, Chen J, Gan B. Liu X, et al. Among authors: yan y. Nat Cell Biol. 2023 Mar;25(3):404-414. doi: 10.1038/s41556-023-01091-2. Epub 2023 Feb 6. Nat Cell Biol. 2023. PMID: 36747082 Free PMC article.
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