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14,113 results
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ATP mediates rapid microglial response to local brain injury in vivo.
Davalos D, Grutzendler J, Yang G, Kim JV, Zuo Y, Jung S, Littman DR, Dustin ML, Gan WB. Davalos D, et al. Among authors: yang g. Nat Neurosci. 2005 Jun;8(6):752-8. doi: 10.1038/nn1472. Epub 2005 May 15. Nat Neurosci. 2005. PMID: 15895084
This rapid chemotactic response can be mimicked by local injection of ATP and can be inhibited by the ATP-hydrolyzing enzyme apyrase or by blockers of G protein-coupled purinergic receptors and connexin channels, which are highly expressed in astrocytes. ...
This rapid chemotactic response can be mimicked by local injection of ATP and can be inhibited by the ATP-hydrolyzing enzyme apyrase or by b …
The P2Y12 receptor regulates microglial activation by extracellular nucleotides.
Haynes SE, Hollopeter G, Yang G, Kurpius D, Dailey ME, Gan WB, Julius D. Haynes SE, et al. Among authors: yang g. Nat Neurosci. 2006 Dec;9(12):1512-9. doi: 10.1038/nn1805. Epub 2006 Nov 19. Nat Neurosci. 2006. PMID: 17115040
Microglia express several purinoceptors, including a G(i)-coupled subtype that has been implicated in ATP- and ADP-mediated migration in vitro. Here we show that microglia from mice lacking G(i)-coupled P2Y(12) receptors exhibit normal baseline motility but are unab …
Microglia express several purinoceptors, including a G(i)-coupled subtype that has been implicated in ATP- and ADP-mediated migration …
Stably maintained dendritic spines are associated with lifelong memories.
Yang G, Pan F, Gan WB. Yang G, et al. Nature. 2009 Dec 17;462(7275):920-4. doi: 10.1038/nature08577. Epub 2009 Nov 29. Nature. 2009. PMID: 19946265 Free PMC article.
Thinned-skull cranial window technique for long-term imaging of the cortex in live mice.
Yang G, Pan F, Parkhurst CN, Grutzendler J, Gan WB. Yang G, et al. Nat Protoc. 2010 Feb;5(2):201-8. doi: 10.1038/nprot.2009.222. Epub 2010 Jan 14. Nat Protoc. 2010. PMID: 20134419 Free PMC article.
Peripheral elevation of TNF-α leads to early synaptic abnormalities in the mouse somatosensory cortex in experimental autoimmune encephalomyelitis.
Yang G, Parkhurst CN, Hayes S, Gan WB. Yang G, et al. Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10306-11. doi: 10.1073/pnas.1222895110. Epub 2013 Jun 3. Proc Natl Acad Sci U S A. 2013. PMID: 23733958 Free PMC article.
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