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AZD1152, a novel and selective aurora B kinase inhibitor, induces growth arrest, apoptosis, and sensitization for tubulin depolymerizing agent or topoisomerase II inhibitor in human acute leukemia cells in vitro and in vivo.
Yang J, Ikezoe T, Nishioka C, Tasaka T, Taniguchi A, Kuwayama Y, Komatsu N, Bandobashi K, Togitani K, Koeffler HP, Taguchi H, Yokoyama A. Yang J, et al. Blood. 2007 Sep 15;110(6):2034-40. doi: 10.1182/blood-2007-02-073700. Epub 2007 May 10. Blood. 2007. PMID: 17495131
A novel treatment strategy targeting Aurora kinases in acute myelogenous leukemia.
Ikezoe T, Yang J, Nishioka C, Tasaka T, Taniguchi A, Kuwayama Y, Komatsu N, Bandobashi K, Togitani K, Koeffler HP, Taguchi H. Ikezoe T, et al. Among authors: yang j. Mol Cancer Ther. 2007 Jun;6(6):1851-7. doi: 10.1158/1535-7163.MCT-07-0067. Epub 2007 May 31. Mol Cancer Ther. 2007. PMID: 17541033
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