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Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling.
Ghoreschi K, Laurence A, Yang XP, Tato CM, McGeachy MJ, Konkel JE, Ramos HL, Wei L, Davidson TS, Bouladoux N, Grainger JR, Chen Q, Kanno Y, Watford WT, Sun HW, Eberl G, Shevach EM, Belkaid Y, Cua DJ, Chen W, O'Shea JJ. Ghoreschi K, et al. Among authors: yang xp. Nature. 2010 Oct 21;467(7318):967-71. doi: 10.1038/nature09447. Nature. 2010. PMID: 20962846 Free PMC article.
T helper 17 cell heterogeneity and pathogenicity in autoimmune disease.
Ghoreschi K, Laurence A, Yang XP, Hirahara K, O'Shea JJ. Ghoreschi K, et al. Among authors: yang xp. Trends Immunol. 2011 Sep;32(9):395-401. doi: 10.1016/j.it.2011.06.007. Epub 2011 Jul 23. Trends Immunol. 2011. PMID: 21782512 Free PMC article. Review.
Helper T-cell differentiation and plasticity: insights from epigenetics.
Hirahara K, Vahedi G, Ghoreschi K, Yang XP, Nakayamada S, Kanno Y, O'Shea JJ, Laurence A. Hirahara K, et al. Among authors: yang xp. Immunology. 2011 Nov;134(3):235-45. doi: 10.1111/j.1365-2567.2011.03483.x. Immunology. 2011. PMID: 21977994 Free PMC article. Review.
Interleukin-27 priming of T cells controls IL-17 production in trans via induction of the ligand PD-L1.
Hirahara K, Ghoreschi K, Yang XP, Takahashi H, Laurence A, Vahedi G, Sciumè G, Hall AO, Dupont CD, Francisco LM, Chen Q, Tanaka M, Kanno Y, Sun HW, Sharpe AH, Hunter CA, O'Shea JJ. Hirahara K, et al. Among authors: yang xp. Immunity. 2012 Jun 29;36(6):1017-30. doi: 10.1016/j.immuni.2012.03.024. Epub 2012 Jun 21. Immunity. 2012. PMID: 22726954 Free PMC article.
The TNF-family ligand TL1A and its receptor DR3 promote T cell-mediated allergic immunopathology by enhancing differentiation and pathogenicity of IL-9-producing T cells.
Richard AC, Tan C, Hawley ET, Gomez-Rodriguez J, Goswami R, Yang XP, Cruz AC, Penumetcha P, Hayes ET, Pelletier M, Gabay O, Walsh M, Ferdinand JR, Keane-Myers A, Choi Y, O'Shea JJ, Al-Shamkhani A, Kaplan MH, Gery I, Siegel RM, Meylan F. Richard AC, et al. Among authors: yang xp. J Immunol. 2015 Apr 15;194(8):3567-82. doi: 10.4049/jimmunol.1401220. Epub 2015 Mar 18. J Immunol. 2015. PMID: 25786692 Free PMC article.
539 results