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In vitro to in vivo extrapolation and species response comparisons for drug-induced liver injury (DILI) using DILIsym™: a mechanistic, mathematical model of DILI.
Howell BA, Yang Y, Kumar R, Woodhead JL, Harrill AH, Clewell HJ 3rd, Andersen ME, Siler SQ, Watkins PB. Howell BA, et al. Among authors: yang y. J Pharmacokinet Pharmacodyn. 2012 Oct;39(5):527-41. doi: 10.1007/s10928-012-9266-0. Epub 2012 Aug 9. J Pharmacokinet Pharmacodyn. 2012. PMID: 22875368
Modeling drug- and chemical-induced hepatotoxicity with systems biology approaches.
Bhattacharya S, Shoda LK, Zhang Q, Woods CG, Howell BA, Siler SQ, Woodhead JL, Yang Y, McMullen P, Watkins PB, Andersen ME. Bhattacharya S, et al. Among authors: yang y. Front Physiol. 2012 Dec 14;3:462. doi: 10.3389/fphys.2012.00462. eCollection 2012. Front Physiol. 2012. PMID: 23248599 Free PMC article.
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