Yang Y - Search Results

1

Pharmacotherapy for Pain in a Family With Inherited Erythromelalgia Guided by Genomic Analysis and Functional Profiling.

Geha P, Yang Y, Estacion M, Schulman BR, Tokuno H, Apkarian AV, Dib-Hajj SD, Waxman SG. Geha P, et al. Among authors: yang y. JAMA Neurol. 2016 Jun 1;73(6):659-67. doi: 10.1001/jamaneurol.2016.0389. JAMA Neurol. 2016. PMID: 27088781

2

The Na(V)1.7 sodium channel: from molecule to man.

Dib-Hajj SD, Yang Y, Black JA, Waxman SG. Dib-Hajj SD, et al. Among authors: yang y. Nat Rev Neurosci. 2013 Jan;14(1):49-62. doi: 10.1038/nrn3404. Epub 2012 Dec 12. Nat Rev Neurosci. 2013. PMID: 23232607 Review.

3

A new Nav1.7 mutation in an erythromelalgia patient.

Estacion M, Yang Y, Dib-Hajj SD, Tyrrell L, Lin Z, Yang Y, Waxman SG. Estacion M, et al. Among authors: yang y. Biochem Biophys Res Commun. 2013 Mar 1;432(1):99-104. doi: 10.1016/j.bbrc.2013.01.079. Epub 2013 Jan 30. Biochem Biophys Res Commun. 2013. PMID: 23376079

4

Molecular architecture of a sodium channel S6 helix: radial tuning of the voltage-gated sodium channel 1.7 activation gate.

Yang Y, Estacion M, Dib-Hajj SD, Waxman SG. Yang Y, et al. J Biol Chem. 2013 May 10;288(19):13741-7. doi: 10.1074/jbc.M113.462366. Epub 2013 Mar 27. J Biol Chem. 2013. PMID: 23536180 Free PMC article.

5

Small-fiber neuropathy Nav1.8 mutation shifts activation to hyperpolarized potentials and increases excitability of dorsal root ganglion neurons.

Huang J, Yang Y, Zhao P, Gerrits MM, Hoeijmakers JG, Bekelaar K, Merkies IS, Faber CG, Dib-Hajj SD, Waxman SG. Huang J, et al. Among authors: yang y. J Neurosci. 2013 Aug 28;33(35):14087-97. doi: 10.1523/JNEUROSCI.2710-13.2013. J Neurosci. 2013. PMID: 23986244 Free PMC article.

6

Multistate structural modeling and voltage-clamp analysis of epilepsy/autism mutation Kv10.2-R327H demonstrate the role of this residue in stabilizing the channel closed state.

Yang Y, Vasylyev DV, Dib-Hajj F, Veeramah KR, Hammer MF, Dib-Hajj SD, Waxman SG. Yang Y, et al. J Neurosci. 2013 Oct 16;33(42):16586-93. doi: 10.1523/JNEUROSCI.2307-13.2013. J Neurosci. 2013. PMID: 24133262 Free PMC article.

7

Depolarized inactivation overcomes impaired activation to produce DRG neuron hyperexcitability in a Nav1.7 mutation in a patient with distal limb pain.

Huang J, Yang Y, Dib-Hajj SD, van Es M, Zhao P, Salomon J, Drenth JP, Waxman SG. Huang J, et al. Among authors: yang y. J Neurosci. 2014 Sep 10;34(37):12328-40. doi: 10.1523/JNEUROSCI.2773-14.2014. J Neurosci. 2014. PMID: 25209274 Free PMC article.

8

The Domain II S4-S5 Linker in Nav1.9: A Missense Mutation Enhances Activation, Impairs Fast Inactivation, and Produces Human Painful Neuropathy.

Han C, Yang Y, de Greef BT, Hoeijmakers JG, Gerrits MM, Verhamme C, Qu J, Lauria G, Merkies IS, Faber CG, Dib-Hajj SD, Waxman SG. Han C, et al. Among authors: yang y. Neuromolecular Med. 2015 Jun;17(2):158-69. doi: 10.1007/s12017-015-8347-9. Epub 2015 Mar 20. Neuromolecular Med. 2015. PMID: 25791876

9

Nav1.7-A1632G Mutation from a Family with Inherited Erythromelalgia: Enhanced Firing of Dorsal Root Ganglia Neurons Evoked by Thermal Stimuli.

Yang Y, Huang J, Mis MA, Estacion M, Macala L, Shah P, Schulman BR, Horton DB, Dib-Hajj SD, Waxman SG. Yang Y, et al. J Neurosci. 2016 Jul 13;36(28):7511-22. doi: 10.1523/JNEUROSCI.0462-16.2016. J Neurosci. 2016. PMID: 27413160 Free PMC article.

10

Familial gain-of-function Na_v1.9 mutation in a painful channelopathy.

Han C, Yang Y, Te Morsche RH, Drenth JP, Politei JM, Waxman SG, Dib-Hajj SD. Han C, et al. Among authors: yang y. J Neurol Neurosurg Psychiatry. 2017 Mar;88(3):233-240. doi: 10.1136/jnnp-2016-313804. Epub 2016 Aug 8. J Neurol Neurosurg Psychiatry. 2017. PMID: 27503742

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