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Defective insulin secretion in hepatocyte nuclear factor 1alpha-deficient mice.
Pontoglio M, Sreenan S, Roe M, Pugh W, Ostrega D, Doyen A, Pick AJ, Baldwin A, Velho G, Froguel P, Levisetti M, Bonner-Weir S, Bell GI, Yaniv M, Polonsky KS. Pontoglio M, et al. Among authors: yaniv m. J Clin Invest. 1998 May 15;101(10):2215-22. doi: 10.1172/JCI2548. J Clin Invest. 1998. PMID: 9593777 Free PMC article.
Embryonic but not postnatal reexpression of hepatocyte nuclear factor 1alpha (HNF1alpha) can reactivate the silent phenylalanine hydroxylase gene in HNF1alpha-deficient hepatocytes.
Viollet B, Yaniv M, Pontoglio M. Viollet B, et al. Among authors: yaniv m. Mol Cell Biol. 2001 Jun;21(11):3662-70. doi: 10.1128/MCB.21.11.3662-3670.2001. Mol Cell Biol. 2001. PMID: 11340160 Free PMC article.
The failure to transcribe the phenylalanine hydroxylase (PAH) gene in the liver of hepatocyte nuclear factor 1alpha (HNF1alpha)-deficient mice correlated with DNA hypermethylation and the presence of an inactive chromatin structure (M. Pontoglio, D. M. Faust, A. Doy …
The failure to transcribe the phenylalanine hydroxylase (PAH) gene in the liver of hepatocyte nuclear factor 1alpha (HNF1alpha)-deficient mi …
307 results