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2,030 results
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Mechanisms of membrane transport of poorly soluble drugs: role of micelles in oral absorption processes.
Yano K, Masaoka Y, Kataoka M, Sakuma S, Yamashita S. Yano K, et al. J Pharm Sci. 2010 Mar;99(3):1336-45. doi: 10.1002/jps.21919. J Pharm Sci. 2010. PMID: 19743502
Age-related pharmacokinetic changes of acetaminophen, antipyrine, diazepam, diphenhydramine, and ofloxacin in male cynomolgus monkeys and beagle dogs.
Koyanagi T, Yamaura Y, Yano K, Kim S, Yamazaki H. Koyanagi T, et al. Among authors: yano k. Xenobiotica. 2014 Oct;44(10):893-901. doi: 10.3109/00498254.2014.903532. Epub 2014 Mar 21. Xenobiotica. 2014. PMID: 24650193
Assessment of absorption potential of poorly water-soluble drugs by using the dissolution/permeation system.
Kataoka M, Yano K, Hamatsu Y, Masaoka Y, Sakuma S, Yamashita S. Kataoka M, et al. Among authors: yano k. Eur J Pharm Biopharm. 2013 Nov;85(3 Pt B):1317-24. doi: 10.1016/j.ejpb.2013.06.018. Epub 2013 Jun 26. Eur J Pharm Biopharm. 2013. PMID: 23811221
[Physicochemical profiling and drug absorption at the drug discovery stage].
Yano K. Yano K. Nihon Yakurigaku Zasshi. 2009 May;133(5):270-3. doi: 10.1254/fpj.133.270. Nihon Yakurigaku Zasshi. 2009. PMID: 19443964 Review. Japanese. No abstract available.
The selective metabotropic glutamate 2/3 receptor agonist MGS0028 reverses isolation rearing-induced abnormal behaviors in mice.
Ago Y, Araki R, Yano K, Kawasaki T, Chaki S, Nakazato A, Onoe H, Hashimoto H, Baba A, Takuma K, Matsuda T. Ago Y, et al. Among authors: yano k. J Pharmacol Sci. 2012;118(2):295-8. doi: 10.1254/jphs.11200sc. Epub 2012 Jan 27. J Pharmacol Sci. 2012. PMID: 22293290
Discovery of new orally active prostaglandin D2 receptor antagonists.
Iwahashi M, Naganawa A, Kinoshita A, Shimabukuro A, Nishiyama T, Ogawa S, Matsunaga Y, Tsukamoto K, Okada Y, Matsumoto R, Nambu F, Oumi R, Odagaki Y, Katagi J, Yano K, Tani K, Nakai H, Toda M. Iwahashi M, et al. Among authors: yano k. Bioorg Med Chem. 2011 Nov 15;19(22):6935-48. doi: 10.1016/j.bmc.2011.08.065. Epub 2011 Sep 2. Bioorg Med Chem. 2011. PMID: 21982795
Age-related changes of hepatic clearances of cytochrome P450 probes, midazolam and R-/S-warfarin in combination with caffeine, omeprazole and metoprolol in cynomolgus monkeys using in vitro-in vivo correlation.
Koyanagi T, Nakanishi Y, Murayama N, Yamaura Y, Ikeda K, Yano K, Uehara S, Utoh M, Kim S, Uno Y, Yamazaki H. Koyanagi T, et al. Among authors: yano k. Xenobiotica. 2015 Apr;45(4):312-21. doi: 10.3109/00498254.2014.979271. Epub 2014 Nov 3. Xenobiotica. 2015. PMID: 25364857
QT PRODACT: in vivo QT assay in the conscious dog for assessing the potential for QT interval prolongation by human pharmaceuticals.
Toyoshima S, Kanno A, Kitayama T, Sekiya K, Nakai K, Haruna M, Mino T, Miyazaki H, Yano K, Yamamoto K. Toyoshima S, et al. Among authors: yano k. J Pharmacol Sci. 2005;99(5):459-71. doi: 10.1254/jphs.qt-a2. J Pharmacol Sci. 2005. PMID: 16493187
Antidepressant-like effects of the glucocorticoid receptor antagonist RU-43044 are associated with changes in prefrontal dopamine in mouse models of depression.
Ago Y, Arikawa S, Yata M, Yano K, Abe M, Takuma K, Matsuda T. Ago Y, et al. Among authors: yano k. Neuropharmacology. 2008 Dec;55(8):1355-63. doi: 10.1016/j.neuropharm.2008.08.026. Epub 2008 Aug 30. Neuropharmacology. 2008. PMID: 18796307
Role of prefrontal dopaminergic neurotransmission in glucocorticoid receptor-mediated modulation of methamphetamine-induced hyperactivity.
Ago Y, Arikawa S, Yata M, Yano K, Abe M, Takuma K, Matsuda T. Ago Y, et al. Among authors: yano k. Synapse. 2009 Jan;63(1):7-14. doi: 10.1002/syn.20575. Synapse. 2009. PMID: 18925659
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