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Analogs of the novel phytohormone, strigolactone, trigger apoptosis and synergize with PARP inhibitors by inducing DNA damage and inhibiting DNA repair.
Croglio MP, Haake JM, Ryan CP, Wang VS, Lapier J, Schlarbaum JP, Dayani Y, Artuso E, Prandi C, Koltai H, Agama K, Pommier Y, Chen Y, Tricoli L, LaRocque JR, Albanese C, Yarden RI. Croglio MP, et al. Among authors: yarden ri. Oncotarget. 2016 Mar 22;7(12):13984-4001. doi: 10.18632/oncotarget.7414. Oncotarget. 2016. PMID: 26910887 Free PMC article.
Functional characterization of a chr13q22.1 pancreatic cancer risk locus reveals long-range interaction and allele-specific effects on DIS3 expression.
Hoskins JW, Ibrahim A, Emmanuel MA, Manmiller SM, Wu Y, O'Neill M, Jia J, Collins I, Zhang M, Thomas JV, Rost LM, Das S, Parikh H, Haake JM, Matters GL, Kurtz RC, Bamlet WR, Klein A, Stolzenberg-Solomon R, Wolpin BM, Yarden R, Wang Z, Smith J, Olson SH, Andresson T, Petersen GM, Amundadottir LT. Hoskins JW, et al. Hum Mol Genet. 2016 Nov 1;25(21):4726-4738. doi: 10.1093/hmg/ddw300. Hum Mol Genet. 2016. PMID: 28172817 Free PMC article.
23 results