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Sleep and periodic leg movement patterns in drug-free patients with Parkinson's disease and multiple system atrophy.
Wetter TC, Collado-Seidel V, Pollmächer T, Yassouridis A, Trenkwalder C. Wetter TC, et al. Sleep. 2000 May 1;23(3):361-7. Sleep. 2000. PMID: 10811380
CONCLUSIONS: Sleep disruption and increased motor activity during REM and non REM sleep are a frequent finding in PD and MSA. An increased PLM index in untreated PD patients may be due to a dopaminergic deficit and is probably not associated with dopaminergic treatm …
CONCLUSIONS: Sleep disruption and increased motor activity during REM and non REM sleep are a frequent finding in PD and MSA. An incr …
The influence of two behavioral regimens on the distribution of sleep and wakefulness in narcoleptic patients.
Volk S, Schulz H, Yassouridis A, Wilde-Frenz J, Simon O. Volk S, et al. Sleep. 1990 Apr;13(2):136-42. doi: 10.1093/sleep/13.2.136. Sleep. 1990. PMID: 2330472
Thirty-two hours (night-day-night) of polygraphic recordings were performed on 14 patients with a diagnosis of narcolepsy-cataplexy. Half of the patients stayed in bed during the day, whereas the other half were seated at a table. Patients were free to nap whenever …
Thirty-two hours (night-day-night) of polygraphic recordings were performed on 14 patients with a diagnosis of narcolepsy-cataplexy. …
The combined dexamethasone/CRH test: a refined laboratory test for psychiatric disorders.
Heuser I, Yassouridis A, Holsboer F. Heuser I, et al. J Psychiatr Res. 1994 Jul-Aug;28(4):341-56. doi: 10.1016/0022-3956(94)90017-5. J Psychiatr Res. 1994. PMID: 7877114
DEX/CRH-test results from 96 patients with major depression (MDE), 11 with a manic episode (MA), 9 with panic disorder (PD), 24 with a schizophrenic psychosis (SP), and 82 healthy control subjects served as the data base for this report. ...This supports the notion …
DEX/CRH-test results from 96 patients with major depression (MDE), 11 with a manic episode (MA), 9 with panic disorder (PD), 24 with …
Pituitary-adrenal-system regulation and psychopathology during amitriptyline treatment in elderly depressed patients and normal comparison subjects.
Heuser IJ, Schweiger U, Gotthardt U, Schmider J, Lammers CH, Dettling M, Yassouridis A, Holsboer F. Heuser IJ, et al. Am J Psychiatry. 1996 Jan;153(1):93-9. doi: 10.1176/ajp.153.1.93. Am J Psychiatry. 1996. PMID: 8540599
METHOD: A combined dexamethasone-suppression/CRH-stimulation (dexamethasone/CRH) test was administered before initiation of amitriptyline treatment and at the end of weeks 1, 3, and 6 of treatment. ...RESULTS: In relation to the comparison subjects, the depressed patients …
METHOD: A combined dexamethasone-suppression/CRH-stimulation (dexamethasone/CRH) test was administered before initiation of amitripty …
Heterogeneity of hypothalamic-pituitary-adrenal system response to a combined dexamethasone-CRH test in multiple sclerosis.
Grasser A, Möller A, Backmund H, Yassouridis A, Holsboer F. Grasser A, et al. Exp Clin Endocrinol Diabetes. 1996;104(1):31-7. doi: 10.1055/s-0029-1211419. Exp Clin Endocrinol Diabetes. 1996. PMID: 8750568
Specifically, the hypothalamic-pituitary-adrenal (HPA) system seems crucial because (a) the inflammatory response is accompanied by HPA activation; (b) animal models with an inherited HPA defect are prone to developing experimental autoimmune encephalitis; and (c) most imp …
Specifically, the hypothalamic-pituitary-adrenal (HPA) system seems crucial because (a) the inflammatory response is accompanied by H …
Trimipramine and imipramine exert different effects on the sleep EEG and on nocturnal hormone secretion during treatment of major depression.
Sonntag A, Rothe B, Guldner J, Yassouridis A, Holsboer F, Steiger A. Sonntag A, et al. Depression. 1996;4(1):1-13. doi: 10.1002/(SICI)1522-7162(1996)4:1<1::AID-DEPR1>3.0.CO;2-S. Depression. 1996. PMID: 9160649 Clinical Trial.
In a 4-week double-blind clinical trial we compared the effects of the tricyclic antidepressants trimipramine and imipramine on the sleep EEG and on nocturnal bormone secretion in 20 male inpatients with major depression. ...Imipramine induced a decrease in growth h …
In a 4-week double-blind clinical trial we compared the effects of the tricyclic antidepressants trimipramine and imipramine on the s …
Modelling and exploring human sleep with event history analysis.
Yassouridis A, Steiger A, Klinger A, Fahrmeir L. Yassouridis A, et al. J Sleep Res. 1999 Mar;8(1):25-36. doi: 10.1046/j.1365-2869.1999.00133.x. J Sleep Res. 1999. PMID: 10188133
We then apply these techniques in a study of 30 healthy male volunteers to assess the mean population intensity and the effects of plasma cortisol concentration on the transition between selected sleep stages as well as the influence of elapsed time in a current REM …
We then apply these techniques in a study of 30 healthy male volunteers to assess the mean population intensity and the effects of pl …
Dehydroepiandrosterone response to the adrenocorticotropin test and the combined dexamethasone and corticotropin-releasing hormone test in patients with multiple sclerosis.
Kümpfel T, Then Bergh F, Friess E, Uhr M, Yassouridis A, Trenkwalder C, Holsboer F. Kümpfel T, et al. Neuroendocrinology. 1999 Dec;70(6):431-8. doi: 10.1159/000054505. Neuroendocrinology. 1999. PMID: 10657736
There was a positive correlation between the EDSS score and maximum cortisol/DHEA ratio (r = 0.45; p = 0.031). As with the hypothalamic-pituitary-adrenal axis system, our results suggest a dysfunction in the DHEA secretion in patients with MS....
There was a positive correlation between the EDSS score and maximum cortisol/DHEA ratio (r = 0.45; p = 0.031). As with the hypothalam …
Behavioral and endocrine response to cholecystokinin tetrapeptide in patients with posttraumatic stress disorder.
Kellner M, Wiedemann K, Yassouridis A, Levengood R, Guo LS, Holsboer F, Yehuda R. Kellner M, et al. Biol Psychiatry. 2000 Jan 15;47(2):107-11. doi: 10.1016/s0006-3223(99)00118-3. Biol Psychiatry. 2000. PMID: 10664826 Clinical Trial.
METHODS: Eight patients with PTSD (DSM-IV) received 50 micrograms CCK-4 intravenously in a placebo-controlled, double-blind balanced design. ...Cortisol was similarly increased in both groups after CCK-4, but PTSD patients showed a more rapid decrease of stimulated …
METHODS: Eight patients with PTSD (DSM-IV) received 50 micrograms CCK-4 intravenously in a placebo-controlled, double-blind balanced …
Clinical characteristics and frequency of the hereditary restless legs syndrome in a population of 300 patients.
Winkelmann J, Wetter TC, Collado-Seidel V, Gasser T, Dichgans M, Yassouridis A, Trenkwalder C. Winkelmann J, et al. Sleep. 2000 Aug 1;23(5):597-602. Sleep. 2000. PMID: 10947027
In all patients a complete neurological examination was performed, and in selected cases electrophysiological examinations and polysomnographic studies. ...If it proved impossible to contact family members to verify reports of a family history, the patients were cla …
In all patients a complete neurological examination was performed, and in selected cases electrophysiological examinations and polyso …
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