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Cacao polyphenols influence the regulation of apolipoprotein in HepG2 and Caco2 cells.
Yasuda A, Natsume M, Osakabe N, Kawahata K, Koga J. Yasuda A, et al. J Agric Food Chem. 2011 Feb 23;59(4):1470-6. doi: 10.1021/jf103820b. Epub 2011 Jan 12. J Agric Food Chem. 2011. PMID: 21226458
Cocoa powder is rich in polyphenols, such as catechins and procyanidins, and has been shown to inhibit low-density lipoprotein (LDL) oxidation and atherogenesis in a variety of models. ...These results elucidate a novel mechanism by which HDL cholesterol levels beco …
Cocoa powder is rich in polyphenols, such as catechins and procyanidins, and has been shown to inhibit low-density lipoprotein (LDL) oxidati …
Dietary supplementation with fructooligosaccharides attenuates airway inflammation related to house dust mite allergen in mice.
Yasuda A, Inoue KI, Sanbongi C, Yanagisawa R, Ichinose T, Yoshikawa T, Takano H. Yasuda A, et al. Int J Immunopathol Pharmacol. 2010 Jul-Sep;23(3):727-35. doi: 10.1177/039463201002300306. Int J Immunopathol Pharmacol. 2010. PMID: 20943042
The purpose of this study is to evaluate the effects of dietary supplementation with FOS on a murine model of allergic airway inflammation induced by the house dust mite allergen Dermatophagoides farinae (Der f). ...In addition, the FOS-supplemented diet reduced the serum …
The purpose of this study is to evaluate the effects of dietary supplementation with FOS on a murine model of allergic airway inflamm …
Cacao liquor proanthocyanidins inhibit lung injury induced by diesel exhaust particles.
Yasuda A, Takano H, Osakabe N, Sanbongi C, Fukuda K, Natsume M, Yanagisawa R, Inoue K, Kato Y, Osawa T, Yoshikawa T. Yasuda A, et al. Int J Immunopathol Pharmacol. 2008 Apr-Jun;21(2):279-88. doi: 10.1177/039463200802100204. Int J Immunopathol Pharmacol. 2008. PMID: 18547470
We carried out a study in mice to investigate the effects of dietary supplementation of CPs on lung injury induced by intratracheal administration of DEPs (500 microg/body). ...These results suggest that CPs inhibit DEP-induced lung injury by reducing oxidative stress, in …
We carried out a study in mice to investigate the effects of dietary supplementation of CPs on lung injury induced by intratracheal a …
Daily cocoa intake reduces the susceptibility of low-density lipoprotein to oxidation as demonstrated in healthy human volunteers.
Osakabe N, Baba S, Yasuda A, Iwamoto T, Kamiyama M, Takizawa T, Itakura H, Kondo K. Osakabe N, et al. Free Radic Res. 2001 Jan;34(1):93-9. doi: 10.1080/10715760100300091. Free Radic Res. 2001. PMID: 11235000
Cocoa powder enhances the level of antioxidative activity in rat plasma.
Baba S, Osakabe N, Natsume M, Yasuda A, Takizawa T, Nakamura T, Terao J. Baba S, et al. Br J Nutr. 2000 Nov;84(5):673-80. Br J Nutr. 2000. PMID: 11177180
All EC metabolites showed a maximum concentration in plasma at 30-60 min post-administration. Glucuronide conjugates of both non-methylated and methylated EC were found in high concentration in plasma. ...
All EC metabolites showed a maximum concentration in plasma at 30-60 min post-administration. Glucuronide conjugates of both non-meth …
Ingestion of proanthocyanidins derived from cacao inhibits diabetes-induced cataract formation in rats.
Osakabe N, Yamagishi M, Natsume M, Yasuda A, Osawa T. Osakabe N, et al. Exp Biol Med (Maywood). 2004 Jan;229(1):33-9. doi: 10.1177/153537020422900104. Exp Biol Med (Maywood). 2004. PMID: 14709774
Starting at 7 days after the streptozotocin challenge, the animals were fed either a normal diet or a diet containing 0.5% w/w CLP over 10 weeks. ...Hydroxynonenal (HNE), a marker of oxidative stress, was detected immunohistochemically in the lenses of the ST …
Starting at 7 days after the streptozotocin challenge, the animals were fed either a normal diet or a diet containing 0.5% w/w …
Catechins and their oligomers linked by C4 --> C8 bonds are major cacao polyphenols and protect low-density lipoprotein from oxidation in vitro.
Osakabe N, Yasuda A, Natsume M, Takizawa T, Terao J, Kondo K. Osakabe N, et al. Exp Biol Med (Maywood). 2002 Jan;227(1):51-6. doi: 10.1177/153537020222700109. Exp Biol Med (Maywood). 2002. PMID: 11788784
Rosmarinic acid, a major polyphenolic component of Perilla frutescens, reduces lipopolysaccharide (LPS)-induced liver injury in D-galactosamine (D-GalN)-sensitized mice.
Osakabe N, Yasuda A, Natsume M, Sanbongi C, Kato Y, Osawa T, Yoshikawa T. Osakabe N, et al. Free Radic Biol Med. 2002 Sep 15;33(6):798-806. doi: 10.1016/s0891-5849(02)00970-x. Free Radic Biol Med. 2002. PMID: 12208367
Cacao procyanidins reduce plasma cholesterol and increase fecal steroid excretion in rats fed a high-cholesterol diet.
Yasuda A, Natsume M, Sasaki K, Baba S, Nakamura Y, Kanegae M, Nagaoka S. Yasuda A, et al. Biofactors. 2008;33(3):211-23. doi: 10.1002/biof.5520330307. Biofactors. 2008. PMID: 19478425
Cocoa powder is rich in polyphenols, such as catechins and oligomeric procyanidins, and has a hypocholesterolemic effect in humans. ...Male Wistar rats were fed a 1% high-cholesterol diet (HC) or a high-cholesterol diet containing 1% polyphenol extract from c …
Cocoa powder is rich in polyphenols, such as catechins and oligomeric procyanidins, and has a hypocholesterolemic effect in humans. . …
Plasma LDL and HDL cholesterol and oxidized LDL concentrations are altered in normo- and hypercholesterolemic humans after intake of different levels of cocoa powder.
Baba S, Natsume M, Yasuda A, Nakamura Y, Tamura T, Osakabe N, Kanegae M, Kondo K. Baba S, et al. J Nutr. 2007 Jun;137(6):1436-41. doi: 10.1093/jn/137.6.1436. J Nutr. 2007. PMID: 17513403 Clinical Trial.
Cocoa powder is rich in polyphenols, such as catechins and procyanidins, and has been shown in a variety of subject models to inhibit oxidized LDL and atherogenesis. ...A stratified analysis was performed on 131 subjects who had a LDL cholesterol concentratio …
Cocoa powder is rich in polyphenols, such as catechins and procyanidins, and has been shown in a variety of subject models to inhibit …
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