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Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway.
Hanafusa H, Torii S, Yasunaga T, Nishida E. Hanafusa H, et al. Among authors: yasunaga t. Nat Cell Biol. 2002 Nov;4(11):850-8. doi: 10.1038/ncb867. Nat Cell Biol. 2002. PMID: 12402043
Xenopus ILK (integrin-linked kinase) is required for morphogenetic movements during gastrulation.
Yasunaga T, Kusakabe M, Yamanaka H, Hanafusa H, Masuyama N, Nishida E. Yasunaga T, et al. Genes Cells. 2005 Apr;10(4):369-79. doi: 10.1111/j.1365-2443.2005.00841.x. Genes Cells. 2005. PMID: 15773899
Shp2, an SH2-containing protein-tyrosine phosphatase, positively regulates receptor tyrosine kinase signaling by dephosphorylating and inactivating the inhibitor Sprouty.
Hanafusa H, Torii S, Yasunaga T, Matsumoto K, Nishida E. Hanafusa H, et al. Among authors: yasunaga t. J Biol Chem. 2004 May 28;279(22):22992-5. doi: 10.1074/jbc.M312498200. Epub 2004 Mar 18. J Biol Chem. 2004. PMID: 15031289
The polarity protein Inturned links NPHP4 to Daam1 to control the subapical actin network in multiciliated cells.
Yasunaga T, Hoff S, Schell C, Helmstädter M, Kretz O, Kuechlin S, Yakulov TA, Engel C, Müller B, Bensch R, Ronneberger O, Huber TB, Lienkamp SS, Walz G. Yasunaga T, et al. J Cell Biol. 2015 Dec 7;211(5):963-73. doi: 10.1083/jcb.201502043. J Cell Biol. 2015. PMID: 26644512 Free PMC article.
Regulation of basal body and ciliary functions by Diversin.
Yasunaga T, Itoh K, Sokol SY. Yasunaga T, et al. Mech Dev. 2011 Sep-Dec;128(7-10):376-86. doi: 10.1016/j.mod.2011.07.004. Epub 2011 Aug 6. Mech Dev. 2011. PMID: 21843637 Free PMC article.
Anks3 interacts with nephronophthisis proteins and is required for normal renal development.
Yakulov TA, Yasunaga T, Ramachandran H, Engel C, Müller B, Hoff S, Dengjel J, Lienkamp SS, Walz G. Yakulov TA, et al. Among authors: yasunaga t. Kidney Int. 2015 Jun;87(6):1191-200. doi: 10.1038/ki.2015.17. Epub 2015 Feb 11. Kidney Int. 2015. PMID: 25671767
ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3.
Hoff S, Halbritter J, Epting D, Frank V, Nguyen TM, van Reeuwijk J, Boehlke C, Schell C, Yasunaga T, Helmstädter M, Mergen M, Filhol E, Boldt K, Horn N, Ueffing M, Otto EA, Eisenberger T, Elting MW, van Wijk JA, Bockenhauer D, Sebire NJ, Rittig S, Vyberg M, Ring T, Pohl M, Pape L, Neuhaus TJ, Elshakhs NA, Koon SJ, Harris PC, Grahammer F, Huber TB, Kuehn EW, Kramer-Zucker A, Bolz HJ, Roepman R, Saunier S, Walz G, Hildebrandt F, Bergmann C, Lienkamp SS. Hoff S, et al. Among authors: yasunaga t. Nat Genet. 2013 Aug;45(8):951-6. doi: 10.1038/ng.2681. Epub 2013 Jun 23. Nat Genet. 2013. PMID: 23793029 Free PMC article.
Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling.
Chaki M, Airik R, Ghosh AK, Giles RH, Chen R, Slaats GG, Wang H, Hurd TW, Zhou W, Cluckey A, Gee HY, Ramaswami G, Hong CJ, Hamilton BA, Cervenka I, Ganji RS, Bryja V, Arts HH, van Reeuwijk J, Oud MM, Letteboer SJ, Roepman R, Husson H, Ibraghimov-Beskrovnaya O, Yasunaga T, Walz G, Eley L, Sayer JA, Schermer B, Liebau MC, Benzing T, Le Corre S, Drummond I, Janssen S, Allen SJ, Natarajan S, O'Toole JF, Attanasio M, Saunier S, Antignac C, Koenekoop RK, Ren H, Lopez I, Nayir A, Stoetzel C, Dollfus H, Massoudi R, Gleeson JG, Andreoli SP, Doherty DG, Lindstrad A, Golzio C, Katsanis N, Pape L, Abboud EB, Al-Rajhi AA, Lewis RA, Omran H, Lee EY, Wang S, Sekiguchi JM, Saunders R, Johnson CA, Garner E, Vanselow K, Andersen JS, Shlomai J, Nurnberg G, Nurnberg P, Levy S, Smogorzewska A, Otto EA, Hildebrandt F. Chaki M, et al. Among authors: yasunaga t. Cell. 2012 Aug 3;150(3):533-48. doi: 10.1016/j.cell.2012.06.028. Cell. 2012. PMID: 22863007 Free PMC article.
The Rac1 regulator ELMO controls basal body migration and docking in multiciliated cells through interaction with Ezrin.
Epting D, Slanchev K, Boehlke C, Hoff S, Loges NT, Yasunaga T, Indorf L, Nestel S, Lienkamp SS, Omran H, Kuehn EW, Ronneberger O, Walz G, Kramer-Zucker A. Epting D, et al. Among authors: yasunaga t. Development. 2015 Jan 1;142(1):174-84. doi: 10.1242/dev.112250. Development. 2015. PMID: 25516973
Evolution of overlapping genes.
Miyata T, Yasunaga T. Miyata T, et al. Among authors: yasunaga t. Nature. 1978 Apr 6;272(5653):532-5. doi: 10.1038/272532a0. Nature. 1978. PMID: 692657 No abstract available.
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