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Persistent antigen at vaccination sites induces tumor-specific CD8⁺ T cell sequestration, dysfunction and deletion.
Hailemichael Y, Dai Z, Jaffarzad N, Ye Y, Medina MA, Huang XF, Dorta-Estremera SM, Greeley NR, Nitti G, Peng W, Liu C, Lou Y, Wang Z, Ma W, Rabinovich B, Sowell RT, Schluns KS, Davis RE, Hwu P, Overwijk WW. Hailemichael Y, et al. Among authors: ye y. Nat Med. 2013 Apr;19(4):465-72. doi: 10.1038/nm.3105. Epub 2013 Mar 3. Nat Med. 2013. PMID: 23455713 Free PMC article.
Antitumor activity mediated by CpG: the route of administration is critical.
Lou Y, Liu C, Lizée G, Peng W, Xu C, Ye Y, Rabinovich BA, Hailemichael Y, Gelbard A, Zhou D, Overwijk WW, Hwu P. Lou Y, et al. Among authors: ye y. J Immunother. 2011 Apr;34(3):279-88. doi: 10.1097/CJI.0b013e31820d2a05. J Immunother. 2011. PMID: 21389870 Free PMC article.
Initiative for Molecular Profiling and Advanced Cancer Therapy (IMPACT): An MD Anderson Precision Medicine Study.
Tsimberidou AM, Hong DS, Ye Y, Cartwright C, Wheler JJ, Falchook GS, Naing A, Fu S, Piha-Paul S, Janku F, Meric-Bernstam F, Hwu P, Kee B, Kies MS, Broaddus R, Mendelsohn J, Hess KR, Kurzrock R. Tsimberidou AM, et al. Among authors: ye y. JCO Precis Oncol. 2017;2017:PO.17.00002. doi: 10.1200/PO.17.00002. Epub 2017 Sep 8. JCO Precis Oncol. 2017. PMID: 29082359 Free PMC article.
A phase I study of hepatic arterial infusion of nab-paclitaxel in combination with intravenous gemcitabine and bevacizumab for patients with advanced cancers and predominant liver metastases.
Tsimberidou AM, Ye Y, Wheler J, Naing A, Hong D, Nwosu U, Hess KR, Wolff RA. Tsimberidou AM, et al. Among authors: ye y. Cancer Chemother Pharmacol. 2013 Apr;71(4):955-63. doi: 10.1007/s00280-013-2088-y. Epub 2013 Feb 3. Cancer Chemother Pharmacol. 2013. PMID: 23377373 Free PMC article. Clinical Trial.
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