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IRAK-4 inhibitors for inflammation.
Wang Z, Wesche H, Stevens T, Walker N, Yeh WC. Wang Z, et al. Among authors: yeh wc. Curr Top Med Chem. 2009;9(8):724-37. doi: 10.2174/156802609789044407. Curr Top Med Chem. 2009. PMID: 19689377 Free PMC article. Review.
Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity.
Salmena L, Lemmers B, Hakem A, Matysiak-Zablocki E, Murakami K, Au PY, Berry DM, Tamblyn L, Shehabeldin A, Migon E, Wakeham A, Bouchard D, Yeh WC, McGlade JC, Ohashi PS, Hakem R. Salmena L, et al. Among authors: yeh wc. Genes Dev. 2003 Apr 1;17(7):883-95. doi: 10.1101/gad.1063703. Epub 2003 Mar 21. Genes Dev. 2003. PMID: 12654726 Free PMC article.
The MAGUK family protein CARD11 is essential for lymphocyte activation.
Hara H, Wada T, Bakal C, Kozieradzki I, Suzuki S, Suzuki N, Nghiem M, Griffiths EK, Krawczyk C, Bauer B, D'Acquisto F, Ghosh S, Yeh WC, Baier G, Rottapel R, Penninger JM. Hara H, et al. Among authors: yeh wc. Immunity. 2003 Jun;18(6):763-75. doi: 10.1016/s1074-7613(03)00148-1. Immunity. 2003. PMID: 12818158
Epstein-Barr virus latent membrane protein 1 activation of NF-kappaB through IRAK1 and TRAF6.
Luftig M, Prinarakis E, Yasui T, Tsichritzis T, Cahir-McFarland E, Inoue J, Nakano H, Mak TW, Yeh WC, Li X, Akira S, Suzuki N, Suzuki S, Mosialos G, Kieff E. Luftig M, et al. Among authors: yeh wc. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15595-600. doi: 10.1073/pnas.2136756100. Epub 2003 Dec 12. Proc Natl Acad Sci U S A. 2003. PMID: 14673102 Free PMC article.
Survival and cardiac remodeling after myocardial infarction are critically dependent on the host innate immune interleukin-1 receptor-associated kinase-4 signaling: a regulator of bone marrow-derived dendritic cells.
Maekawa Y, Mizue N, Chan A, Shi Y, Liu Y, Dawood S, Chen M, Dawood F, de Couto G, Li GH, Suzuki N, Yeh WC, Gramolini A, Medin JA, Liu PP. Maekawa Y, et al. Among authors: yeh wc. Circulation. 2009 Oct 6;120(14):1401-14. doi: 10.1161/CIRCULATIONAHA.109.865956. Epub 2009 Sep 21. Circulation. 2009. PMID: 19770394
DNA damage- and stress-induced apoptosis occurs independently of PIDD.
Kim IR, Murakami K, Chen NJ, Saibil SD, Matysiak-Zablocki E, Elford AR, Bonnard M, Benchimol S, Jurisicova A, Yeh WC, Ohashi PS. Kim IR, et al. Among authors: yeh wc. Apoptosis. 2009 Sep;14(9):1039-49. doi: 10.1007/s10495-009-0375-1. Apoptosis. 2009. PMID: 19575295
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