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Tissue-type plasminogen activator in the ischemic brain: more than a thrombolytic.
Yepes M, Roussel BD, Ali C, Vivien D. Yepes M, et al. Trends Neurosci. 2009 Jan;32(1):48-55. doi: 10.1016/j.tins.2008.09.006. Epub 2008 Oct 27. Trends Neurosci. 2009. PMID: 18963068 Review.
[Thrombolytics and neuroprotective agents in the treatment of the patient with an acute cerebrovascular ischemic accident].
Yepes MS. Yepes MS. Rev Neurol. 2001 Feb 1-15;32(3):259-66. Rev Neurol. 2001. PMID: 11310282 Review. Spanish.
Regulation of seizure spreading by neuroserpin and tissue-type plasminogen activator is plasminogen-independent.
Yepes M, Sandkvist M, Coleman TA, Moore E, Wu JY, Mitola D, Bugge TH, Lawrence DA. Yepes M, et al. J Clin Invest. 2002 Jun;109(12):1571-8. doi: 10.1172/JCI14308. J Clin Invest. 2002. PMID: 12070304 Free PMC article.
Adjuvant treatment with neuroserpin increases the therapeutic window for tissue-type plasminogen activator administration in a rat model of embolic stroke.
Zhang Z, Zhang L, Yepes M, Jiang Q, Li Q, Arniego P, Coleman TA, Lawrence DA, Chopp M. Zhang Z, et al. Among authors: yepes m. Circulation. 2002 Aug 6;106(6):740-5. doi: 10.1161/01.cir.0000023942.10849.41. Circulation. 2002. PMID: 12163437
Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein.
Yepes M, Sandkvist M, Moore EG, Bugge TH, Strickland DK, Lawrence DA. Yepes M, et al. J Clin Invest. 2003 Nov;112(10):1533-40. doi: 10.1172/JCI19212. J Clin Invest. 2003. PMID: 14617754 Free PMC article.
Neuroserpin: a selective inhibitor of tissue-type plasminogen activator in the central nervous system.
Yepes M, Lawrence DA. Yepes M, et al. Thromb Haemost. 2004 Mar;91(3):457-64. doi: 10.1160/TH03-12-0766. Thromb Haemost. 2004. PMID: 14983220 Review.
Tissue-type plasminogen activator and neuroserpin: a well-balanced act in the nervous system?
Yepes M, Lawrence DA. Yepes M, et al. Trends Cardiovasc Med. 2004 Jul;14(5):173-80. doi: 10.1016/j.tcm.2004.03.004. Trends Cardiovasc Med. 2004. PMID: 15261888 Review.
New functions for an old enzyme: nonhemostatic roles for tissue-type plasminogen activator in the central nervous system.
Yepes M, Lawrence DA. Yepes M, et al. Exp Biol Med (Maywood). 2004 Dec;229(11):1097-104. doi: 10.1177/153537020422901103. Exp Biol Med (Maywood). 2004. PMID: 15564435 Review.
Tumor necrosis factor-like weak inducer of apoptosis increases the permeability of the neurovascular unit through nuclear factor-kappa B pathway activation.
Polavarapu R, Gongora MC, Winkles JA, Yepes M. Polavarapu R, et al. Among authors: yepes m. J Neurosci. 2005 Nov 2;25(44):10094-100. doi: 10.1523/JNEUROSCI.3382-05.2005. J Neurosci. 2005. PMID: 16267216 Free PMC article.
TWEAK-Fn14 pathway inhibition protects the integrity of the neurovascular unit during cerebral ischemia.
Zhang X, Winkles JA, Gongora MC, Polavarapu R, Michaelson JS, Hahm K, Burkly L, Friedman M, Li XJ, Yepes M. Zhang X, et al. Among authors: yepes m. J Cereb Blood Flow Metab. 2007 Mar;27(3):534-44. doi: 10.1038/sj.jcbfm.9600368. Epub 2006 Jul 12. J Cereb Blood Flow Metab. 2007. PMID: 16835630
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