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Broad-Spectrum Adaptive Antibiotic Resistance Associated with Pseudomonas aeruginosa Mucin-Dependent Surfing Motility.
Sun E, Gill EE, Falsafi R, Yeung A, Liu S, Hancock REW. Sun E, et al. Antimicrob Agents Chemother. 2018 Aug 27;62(9):e00848-18. doi: 10.1128/AAC.00848-18. Print 2018 Sep. Antimicrob Agents Chemother. 2018. PMID: 29967020 Free PMC article.
Surfing motility is a novel form of surface adaptation exhibited by the nosocomial pathogen Pseudomonas aeruginosa in the presence of the glycoprotein mucin, which is found in high abundance at mucosal surfaces, especially those of the lungs of cystic fibrosis and bronchie …
Surfing motility is a novel form of surface adaptation exhibited by the nosocomial pathogen Pseudomonas aeruginosa in the presence of the gl …
Therapeutic potential of host defense peptides in antibiotic-resistant infections.
Afacan NJ, Yeung AT, Pena OM, Hancock RE. Afacan NJ, et al. Curr Pharm Des. 2012;18(6):807-19. doi: 10.2174/138161212799277617. Curr Pharm Des. 2012. PMID: 22236127 Review.
Novel roles for two-component regulatory systems in cytotoxicity and virulence-related properties in Pseudomonas aeruginosa.
Gellatly SL, Bains M, Breidenstein EBM, Strehmel J, Reffuveille F, Taylor PK, Yeung ATY, Overhage J, Hancock REW. Gellatly SL, et al. Among authors: yeung aty. AIMS Microbiol. 2018 Mar 8;4(1):173-191. doi: 10.3934/microbiol.2018.1.173. eCollection 2018. AIMS Microbiol. 2018. PMID: 31294209 Free PMC article.
Requirement of the Pseudomonas aeruginosa CbrA sensor kinase for full virulence in a murine acute lung infection model.
Yeung AT, Janot L, Pena OM, Neidig A, Kukavica-Ibrulj I, Hilchie A, Levesque RC, Overhage J, Hancock RE. Yeung AT, et al. Infect Immun. 2014 Mar;82(3):1256-67. doi: 10.1128/IAI.01527-13. Epub 2013 Dec 30. Infect Immun. 2014. PMID: 24379284 Free PMC article.
TypA is involved in virulence, antimicrobial resistance and biofilm formation in Pseudomonas aeruginosa.
Neidig A, Yeung AT, Rosay T, Tettmann B, Strempel N, Rueger M, Lesouhaitier O, Overhage J. Neidig A, et al. BMC Microbiol. 2013 Apr 9;13:77. doi: 10.1186/1471-2180-13-77. BMC Microbiol. 2013. PMID: 23570569 Free PMC article.
Mucin promotes rapid surface motility in Pseudomonas aeruginosa.
Yeung AT, Parayno A, Hancock RE. Yeung AT, et al. mBio. 2012 May 1;3(3):e00073-12. doi: 10.1128/mBio.00073-12. Print 2012. mBio. 2012. PMID: 22550036 Free PMC article.
P. aeruginosa is known to swim within 0.3% (wt/vol) agar and swarm on the surface at 0.5% (wt/vol) agar with amino acids as a weak nitrogen source. ...Interestingly, bacterial cells at the thick edge appeared piled up and lacked flagella, while cells at the m …
P. aeruginosa is known to swim within 0.3% (wt/vol) agar and swarm on the surface at 0.5% (wt/vol) agar with amino acids as a weak ni …
Swarming of Pseudomonas aeruginosa is controlled by a broad spectrum of transcriptional regulators, including MetR.
Yeung AT, Torfs EC, Jamshidi F, Bains M, Wiegand I, Hancock RE, Overhage J. Yeung AT, et al. J Bacteriol. 2009 Sep;191(18):5592-602. doi: 10.1128/JB.00157-09. Epub 2009 Jul 10. J Bacteriol. 2009. PMID: 19592586 Free PMC article.
Multifunctional cationic host defence peptides and their clinical applications.
Yeung AT, Gellatly SL, Hancock RE. Yeung AT, et al. Cell Mol Life Sci. 2011 Jul;68(13):2161-76. doi: 10.1007/s00018-011-0710-x. Epub 2011 May 15. Cell Mol Life Sci. 2011. PMID: 21573784 Review.
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