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GABA(A) receptors as molecular sites of ethanol action. Direct or indirect actions?
Aguayo LG, Peoples RW, Yeh HH, Yevenes GE. Aguayo LG, et al. Among authors: yevenes ge. Curr Top Med Chem. 2002 Aug;2(8):869-85. doi: 10.2174/1568026023393426. Curr Top Med Chem. 2002. PMID: 12171577 Review.
Glycine receptors involved in synaptic transmission are selectively regulated by the cytoskeleton in mouse spinal neurons.
van Zundert B, Alvarez FJ, Yevenes GE, Cárcamo JG, Vera JC, Aguayo LG. van Zundert B, et al. Among authors: yevenes ge. J Neurophysiol. 2002 Jan;87(1):640-4. doi: 10.1152/jn.00455.2001. J Neurophysiol. 2002. PMID: 11784780
Modulation of glycine-activated ion channel function by G-protein betagamma subunits.
Yevenes GE, Peoples RW, Tapia JC, Parodi J, Soto X, Olate J, Aguayo LG. Yevenes GE, et al. Nat Neurosci. 2003 Aug;6(8):819-24. doi: 10.1038/nn1095. Nat Neurosci. 2003. PMID: 12858180
Molecular determinants for G protein betagamma modulation of ionotropic glycine receptors.
Yevenes GE, Moraga-Cid G, Guzmán L, Haeger S, Oliveira L, Olate J, Schmalzing G, Aguayo LG. Yevenes GE, et al. J Biol Chem. 2006 Dec 22;281(51):39300-7. doi: 10.1074/jbc.M608272200. Epub 2006 Oct 12. J Biol Chem. 2006. PMID: 17040914
A selective G betagamma-linked intracellular mechanism for modulation of a ligand-gated ion channel by ethanol.
Yevenes GE, Moraga-Cid G, Peoples RW, Schmalzing G, Aguayo LG. Yevenes GE, et al. Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20523-8. doi: 10.1073/pnas.0806257105. Epub 2008 Dec 12. Proc Natl Acad Sci U S A. 2008. PMID: 19074265 Free PMC article.
Blockade of ethanol-induced potentiation of glycine receptors by a peptide that interferes with Gbetagamma binding.
Guzman L, Moraga-Cid G, Avila A, Figueroa M, Yevenes GE, Fuentealba J, Aguayo LG. Guzman L, et al. Among authors: yevenes ge. J Pharmacol Exp Ther. 2009 Dec;331(3):933-9. doi: 10.1124/jpet.109.160440. Epub 2009 Sep 22. J Pharmacol Exp Ther. 2009. PMID: 19773530 Free PMC article.
Molecular requirements for ethanol differential allosteric modulation of glycine receptors based on selective Gbetagamma modulation.
Yevenes GE, Moraga-Cid G, Avila A, Guzmán L, Figueroa M, Peoples RW, Aguayo LG. Yevenes GE, et al. J Biol Chem. 2010 Sep 24;285(39):30203-13. doi: 10.1074/jbc.M110.134676. Epub 2010 Jul 20. J Biol Chem. 2010. PMID: 20647311 Free PMC article.
Potentiation and inhibition of glycine receptors by tutin.
Fuentealba J, Muñoz B, Yévenes G, Moraga-Cid G, Pérez C, Guzmán L, Rigo JM, Aguayo LG. Fuentealba J, et al. Neuropharmacology. 2011 Feb-Mar;60(2-3):453-9. doi: 10.1016/j.neuropharm.2010.10.023. Epub 2010 Oct 31. Neuropharmacology. 2011. PMID: 21044637
A Single phenylalanine residue in the main intracellular loop of α1 γ-aminobutyric acid type A and glycine receptors influences their sensitivity to propofol.
Moraga-Cid G, Yevenes GE, Schmalzing G, Peoples RW, Aguayo LG. Moraga-Cid G, et al. Among authors: yevenes ge. Anesthesiology. 2011 Sep;115(3):464-73. doi: 10.1097/ALN.0b013e31822550f7. Anesthesiology. 2011. PMID: 21673564 Free PMC article.
Activated G protein α s subunits increase the ethanol sensitivity of human glycine receptors.
Yévenes GE, Moraga-Cid G, Romo X, Aguayo LG. Yévenes GE, et al. J Pharmacol Exp Ther. 2011 Nov;339(2):386-93. doi: 10.1124/jpet.111.184408. Epub 2011 Aug 5. J Pharmacol Exp Ther. 2011. PMID: 21821696 Free PMC article.
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