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MicroRNA-21 Aggravates Cyst Growth in a Model of Polycystic Kidney Disease.
Lakhia R, Hajarnis S, Williams D, Aboudehen K, Yheskel M, Xing C, Hatley ME, Torres VE, Wallace DP, Patel V. Lakhia R, et al. Among authors: yheskel m. J Am Soc Nephrol. 2016 Aug;27(8):2319-30. doi: 10.1681/ASN.2015060634. Epub 2015 Dec 17. J Am Soc Nephrol. 2016. PMID: 26677864 Free PMC article.
microRNA-17 family promotes polycystic kidney disease progression through modulation of mitochondrial metabolism.
Hajarnis S, Lakhia R, Yheskel M, Williams D, Sorourian M, Liu X, Aboudehen K, Zhang S, Kersjes K, Galasso R, Li J, Kaimal V, Lockton S, Davis S, Flaten A, Johnson JA, Holland WL, Kusminski CM, Scherer PE, Harris PC, Trudel M, Wallace DP, Igarashi P, Lee EC, Androsavich JR, Patel V. Hajarnis S, et al. Among authors: yheskel m. Nat Commun. 2017 Feb 16;8:14395. doi: 10.1038/ncomms14395. Nat Commun. 2017. PMID: 28205547 Free PMC article.
Therapeutic microRNAs in polycystic kidney disease.
Yheskel M, Patel V. Yheskel M, et al. Curr Opin Nephrol Hypertens. 2017 Jul;26(4):282-289. doi: 10.1097/MNH.0000000000000333. Curr Opin Nephrol Hypertens. 2017. PMID: 28399020 Free PMC article. Review.
Modulation of polycystic kidney disease by non-coding RNAs.
Ramalingam H, Yheskel M, Patel V. Ramalingam H, et al. Among authors: yheskel m. Cell Signal. 2020 Jul;71:109548. doi: 10.1016/j.cellsig.2020.109548. Epub 2020 Jan 23. Cell Signal. 2020. PMID: 31982550 Free PMC article. Review.
Discovery and preclinical evaluation of anti-miR-17 oligonucleotide RGLS4326 for the treatment of polycystic kidney disease.
Lee EC, Valencia T, Allerson C, Schairer A, Flaten A, Yheskel M, Kersjes K, Li J, Gatto S, Takhar M, Lockton S, Pavlicek A, Kim M, Chu T, Soriano R, Davis S, Androsavich JR, Sarwary S, Owen T, Kaplan J, Liu K, Jang G, Neben S, Bentley P, Wright T, Patel V. Lee EC, et al. Among authors: yheskel m. Nat Commun. 2019 Sep 12;10(1):4148. doi: 10.1038/s41467-019-11918-y. Nat Commun. 2019. PMID: 31515477 Free PMC article.