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Type 2 diabetes risk gene Dusp8 regulates hypothalamic Jnk signaling and insulin sensitivity.
Schriever SC, Kabra DG, Pfuhlmann K, Baumann P, Baumgart EV, Nagler J, Seebacher F, Harrison L, Irmler M, Kullmann S, Corrêa-da-Silva F, Giesert F, Jain R, Schug H, Castel J, Martinez S, Wu M, Häring HU, Hrabe de Angelis M, Beckers J, Müller TD, Stemmer K, Wurst W, Rozman J, Nogueiras R, De Angelis M, Molkentin JD, Krahmer N, Yi CX, Schmidt MV, Luquet S, Heni M, Tschoep MH, Pfluger PT. Schriever SC, et al. Among authors: yi cx. J Clin Invest. 2020 Aug 11:136363. doi: 10.1172/JCI136363. Online ahead of print. J Clin Invest. 2020. PMID: 32780722
Lipid Droplets accumulate in the hypothalamus of mice and humans with and without metabolic diseases.
Maya-Monteiro CM, Corrêa-da-Silva F, Hofmann SS, Hesselink MKC, la Fleur SE, Yi CX. Maya-Monteiro CM, et al. Among authors: yi cx. Neuroendocrinology. 2020 May 18. doi: 10.1159/000508735. Online ahead of print. Neuroendocrinology. 2020. PMID: 32422642
The Iminosugar AMP-DNM Improves Satiety and Activates Brown Adipose Tissue Through GLP1.
Herrera Moro Chao D, Wang Y, Foppen E, Ottenhoff R, van Roomen C, Parlevliet ET, van Eijk M, Verhoek M, Boot R, Marques AR, Scheij S, Mirzaian M, Kooijman S, Jansen K, Wang D, Mergen C, Seeley RJ, Tschöp MH, Overkleeft H, Rensen PCN, Kalsbeek A, Aerts JMFG, Yi CX. Herrera Moro Chao D, et al. Among authors: yi cx. Diabetes. 2019 Dec;68(12):2223-2234. doi: 10.2337/db19-0049. Epub 2019 Oct 2. Diabetes. 2019. PMID: 31578192 Free article.
Time-Restricted Feeding Improves Glucose Tolerance in Rats, but Only When in Line With the Circadian Timing System.
de Goede P, Foppen E, Ritsema WIGR, Korpel NL, Yi CX, Kalsbeek A. de Goede P, et al. Among authors: yi cx. Front Endocrinol (Lausanne). 2019 Aug 21;10:554. doi: 10.3389/fendo.2019.00554. eCollection 2019. Front Endocrinol (Lausanne). 2019. PMID: 31496992 Free PMC article.
Loss of arginine vasopressin- and vasoactive intestinal polypeptide-containing neurons and glial cells in the suprachiasmatic nucleus of individuals with type 2 diabetes.
Hogenboom R, Kalsbeek MJ, Korpel NL, de Goede P, Koenen M, Buijs RM, Romijn JA, Swaab DF, Kalsbeek A, Yi CX. Hogenboom R, et al. Among authors: yi cx. Diabetologia. 2019 Nov;62(11):2088-2093. doi: 10.1007/s00125-019-4953-7. Epub 2019 Jul 20. Diabetologia. 2019. PMID: 31327049 Free PMC article.
Diet-Induced Obesity Disturbs Microglial Immunometabolism in a Time-of-Day Manner.
Milanova IV, Kalsbeek MJT, Wang XL, Korpel NL, Stenvers DJ, Wolff SEC, de Goede P, Heijboer AC, Fliers E, la Fleur SE, Kalsbeek A, Yi CX. Milanova IV, et al. Among authors: yi cx. Front Endocrinol (Lausanne). 2019 Jun 26;10:424. doi: 10.3389/fendo.2019.00424. eCollection 2019. Front Endocrinol (Lausanne). 2019. PMID: 31316470 Free PMC article.
Corrigendum to "Deficiency of leptin receptor in myeloid cells disrupts hypothalamic metabolic circuits and causes body weight increase" [Molecular Metabolism 7 (2018) 155-160].
Gao Y, Vidal-Itriago A, Milanova I, Korpel NL, Kalsbeek MJ, Tom RZ, Kalsbeek A, Hofmann SM, Yi CX. Gao Y, et al. Among authors: yi cx. Mol Metab. 2019 Feb;20:205. doi: 10.1016/j.molmet.2018.12.006. Epub 2018 Dec 24. Mol Metab. 2019. PMID: 30594493 Free PMC article. No abstract available.
Role of astrocytes, microglia, and tanycytes in brain control of systemic metabolism.
García-Cáceres C, Balland E, Prevot V, Luquet S, Woods SC, Koch M, Horvath TL, Yi CX, Chowen JA, Verkhratsky A, Araque A, Bechmann I, Tschöp MH. García-Cáceres C, et al. Among authors: yi cx. Nat Neurosci. 2019 Jan;22(1):7-14. doi: 10.1038/s41593-018-0286-y. Epub 2018 Dec 10. Nat Neurosci. 2019. PMID: 30531847 Review.
Streptozotocin-induced β-cell damage, high fat diet, and metformin administration regulate Hes3 expression in the adult mouse brain.
Nikolakopoulou P, Chatzigeorgiou A, Kourtzelis I, Toutouna L, Masjkur J, Arps-Forker C, Poser SW, Rozman J, Rathkolb B, Aguilar-Pimentel JA; German Mouse Clinic Consortium, Wolf E, Klingenspor M, Ollert M, Schmidt-Weber C, Fuchs H, Gailus-Durner V, Hrabe de Angelis M, Tsata V, Monasor LS, Troullinaki M, Witt A, Anastasiou V, Chrousos G, Yi CX, García-Cáceres C, Tschöp MH, Bornstein SR, Androutsellis-Theotokis A. Nikolakopoulou P, et al. Among authors: yi cx. Sci Rep. 2018 Jul 27;8(1):11335. doi: 10.1038/s41598-018-29434-2. Sci Rep. 2018. PMID: 30054579 Free PMC article.
Circulating HDL levels control hypothalamic astrogliosis via apoA-I.
Götz A, Lehti M, Donelan E, Striese C, Cucuruz S, Sachs S, Yi CX, Woods SC, Wright SD, Müller TD, Tschöp MH, Gao Y, Hofmann SM. Götz A, et al. Among authors: yi cx. J Lipid Res. 2018 Sep;59(9):1649-1659. doi: 10.1194/jlr.M085456. Epub 2018 Jul 10. J Lipid Res. 2018. PMID: 29991652 Free PMC article.
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