Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2022 1
2023 6
2024 2
2025 2

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

6 results

Results by year

Filters applied: . Clear all
Page 1
Chalcone-based imidazo[2,1-b]thiazole derivatives: synthesis, crystal structure, potent anticancer activity, and computational studies.
Dadou S, Altay A, Baydere C, Anouar EH, Türkmenoğlu B, Koudad M, Dege N, Oussaid A, Benchat N, Karrouchi K. Dadou S, et al. J Biomol Struct Dyn. 2025 Jan;43(1):261-276. doi: 10.1080/07391102.2023.2280756. Epub 2023 Nov 27. J Biomol Struct Dyn. 2025. PMID: 38009853
In this work, two novel chalcone-based imidazothiazole derivatives ITC-1 and ITC-2 were synthesized and characterized by (1)H NMR, (13)C NMR and high-resolution mass spectrometry with electrospray ionization, and chemical structure of ITC-1 was confirmed by s …
In this work, two novel chalcone-based imidazothiazole derivatives ITC-1 and ITC-2 were synthesized and characterized by (1)H …
Synthesis, characterization and docking studies of benzenesulfonamide derivatives containing 1,2,3-triazole as potential inhibitor of carbonic anhydrase I-II enzymes.
Güngör SA, Köse M, Tümer M, Türkeş C, Beydemir Ş. Güngör SA, et al. J Biomol Struct Dyn. 2023 Dec;41(20):10919-10929. doi: 10.1080/07391102.2022.2159531. Epub 2022 Dec 28. J Biomol Struct Dyn. 2023. PMID: 36576122
In this study, a series of benzenesulfonamide derivatives (9a-h) containing 1,2,3-triazole-moiety were designed, synthesized and their structures were characterized by spectroscopic methods. ...
In this study, a series of benzenesulfonamide derivatives (9a-h) containing 1,2,3-triazole-moiety were designed, synthesized and thei …
Development of novel 1,2,4-triazole containing compounds with anticancer and potent anti-CB1 activity.
Yıldırım S, Ayvaz A, Mermer A, Kocabaş F. Yıldırım S, et al. J Biomol Struct Dyn. 2024 May;42(8):3862-3873. doi: 10.1080/07391102.2023.2239909. Epub 2023 Jul 27. J Biomol Struct Dyn. 2024. PMID: 37501561
Due to their dipole character, hydrogen bonding capacity, rigidity and solubility, 1,2,4-triazoles are particularly effective pharmacophores, interacting with biological receptors with high affinity. ...Cell cycle analysis showed that the effect of compounds 5e-g in cancer …
Due to their dipole character, hydrogen bonding capacity, rigidity and solubility, 1,2,4-triazoles are particularly effective pharmac …
Biological evaluations and computational studies of newly synthesized thymol-based Schiff bases as anticancer, antimicrobial and antioxidant agents.
Sahin D, Kepekci RA, Türkmenoğlu B, Akkoc S. Sahin D, et al. J Biomol Struct Dyn. 2023 Dec 26:1-15. doi: 10.1080/07391102.2023.2297813. Online ahead of print. J Biomol Struct Dyn. 2023. PMID: 38147403
One of the molecules (4a) was found to have a higher efficacy towards the colon cancer cell line (DLD-1) with an IC(50) value of 12.39 M and the other (4c) towards the prostate cancer cell line (PC3) with an IC(50) value of 7.67 M than the positive control drug cisplatin. …
One of the molecules (4a) was found to have a higher efficacy towards the colon cancer cell line (DLD-1) with an IC(50) value of 12.3 …
Novel beta-lactam substituted benzenesulfonamides: in vitro enzyme inhibition, cytotoxic activity and in silico interactions.
Güleç Ö, Türkeş C, Arslan M, Demir Y, Dincer B, Ece A, Beydemir Ş. Güleç Ö, et al. J Biomol Struct Dyn. 2024 Aug;42(12):6359-6377. doi: 10.1080/07391102.2023.2240889. Epub 2023 Aug 4. J Biomol Struct Dyn. 2024. PMID: 37540185
The compounds were characterized using IR, (1)H NMR, (13)C NMR and elemental analysis techniques. These newly synthesized compounds were tested for their ability to inhibit the activity of two carbonic anhydrases (hCA) isoforms, I and II, and acetylcholinesterase (AChE) in …
The compounds were characterized using IR, (1)H NMR, (13)C NMR and elemental analysis techniques. These newly synthesized compounds w …
The synthesis, carbonic anhydrase and acetylcholinesterase inhibition effects of sulfonyl chloride moiety containing oxazolidinones using an intramolecular aza-Michael addition.
Yıldırım A, Atmaca U, Şahin E, Taslimi P, Taskin-Tok T, Çelik M, Gülçin İ. Yıldırım A, et al. J Biomol Struct Dyn. 2025 Feb;43(2):1052-1067. doi: 10.1080/07391102.2023.2291163. Epub 2023 Dec 15. J Biomol Struct Dyn. 2025. PMID: 38100567
All the synthesized compounds had potent inhibition effects with Ki values in the range of 13.57 0.98 - 53.60 6.81 M against hCA I and 9.96 1.02 - 46.35 3.83 M against hCA II in comparison to the acetazolamide (AZA) (Ki = 50.46 6.17 M for hCA I) and for hCA II (Ki = 41.31 …
All the synthesized compounds had potent inhibition effects with Ki values in the range of 13.57 0.98 - 53.60 6.81 M against hCA I and 9.96 …