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Serine protease inhibitor Kazal type 1 (SPINK1) downregulates E-cadherin and induces EMT of hepatoma cells to promote hepatocellular carcinoma metastasis via the MEK/ERK signaling pathway.
Ying HY, Gong CJ, Feng Y, Jing DD, Lu LG. Ying HY, et al. J Dig Dis. 2017 Jun;18(6):349-358. doi: 10.1111/1751-2980.12486. J Dig Dis. 2017. PMID: 28544403
Novel matrine derivative MD-1 attenuates hepatic fibrosis by inhibiting EGFR activation of hepatic stellate cells.
Feng Y, Ying HY, Qu Y, Cai XB, Xu MY, Lu LG. Feng Y, et al. Among authors: ying hy. Protein Cell. 2016 Sep;7(9):662-72. doi: 10.1007/s13238-016-0285-2. Epub 2016 Jun 24. Protein Cell. 2016. PMID: 27342773 Free PMC article.
Histone methyltransferase SETDB1 regulates liver cancer cell growth through methylation of p53.
Fei Q, Shang K, Zhang J, Chuai S, Kong D, Zhou T, Fu S, Liang Y, Li C, Chen Z, Zhao Y, Yu Z, Huang Z, Hu M, Ying H, Chen Z, Zhang Y, Xing F, Zhu J, Xu H, Zhao K, Lu C, Atadja P, Xiao ZX, Li E, Shou J. Fei Q, et al. Among authors: ying h. Nat Commun. 2015 Oct 16;6:8651. doi: 10.1038/ncomms9651. Nat Commun. 2015. PMID: 26471002 Free PMC article.
PPARgamma insufficiency promotes follicular thyroid carcinogenesis via activation of the nuclear factor-kappaB signaling pathway.
Kato Y, Ying H, Zhao L, Furuya F, Araki O, Willingham MC, Cheng SY. Kato Y, et al. Among authors: ying h. Oncogene. 2006 May 4;25(19):2736-47. doi: 10.1038/sj.onc.1209299. Oncogene. 2006. PMID: 16314832
Cloning and characterization of F-LANa, upregulated in human liver cancer.
Ying H, Yu Y, Xu Y. Ying H, et al. Biochem Biophys Res Commun. 2001 Aug 17;286(2):394-400. doi: 10.1006/bbrc.2001.5390. Biochem Biophys Res Commun. 2001. PMID: 11500051
ARF promotes accumulation of retinoblastoma protein through inhibition of MDM2.
Chang DL, Qiu W, Ying H, Zhang Y, Chen CY, Xiao ZX. Chang DL, et al. Among authors: ying h. Oncogene. 2007 Jul 12;26(32):4627-34. doi: 10.1038/sj.onc.1210254. Epub 2007 Feb 5. Oncogene. 2007. PMID: 17297463
Pten and p53 converge on c-Myc to control differentiation, self-renewal, and transformation of normal and neoplastic stem cells in glioblastoma.
Zheng H, Ying H, Yan H, Kimmelman AC, Hiller DJ, Chen AJ, Perry SR, Tonon G, Chu GC, Ding Z, Stommel JM, Dunn KL, Wiedemeyer R, You MJ, Brennan C, Wang YA, Ligon KL, Wong WH, Chin L, dePinho RA. Zheng H, et al. Among authors: ying h. Cold Spring Harb Symp Quant Biol. 2008;73:427-37. doi: 10.1101/sqb.2008.73.047. Epub 2009 Jan 15. Cold Spring Harb Symp Quant Biol. 2008. PMID: 19150964
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