Triple-negative breast cancer and PTEN (phosphatase and tensin homologue) loss are predictors of BRCA1 germline mutations in women with early-onset and familial breast cancer, but not in women with isolated late-onset breast cancer.
Breast Cancer Res. 2012 Nov 2;14(6):R142. doi: 10.1186/bcr3347. Breast Cancer Res. 2012. PMID: 23116406 Free PMC article.