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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1935 1
1936 1
1945 7
1946 1
1947 5
1948 6
1949 12
1950 7
1951 7
1952 3
1953 11
1954 63
1955 236
1956 446
1957 431
1958 349
1959 275
1960 266
1961 249
1962 308
1963 466
1964 613
1965 464
1966 469
1967 615
1968 593
1969 643
1970 553
1971 572
1972 553
1973 589
1974 590
1975 541
1976 464
1977 421
1978 368
1979 418
1980 376
1981 396
1982 472
1983 532
1984 647
1985 691
1986 639
1987 632
1988 624
1989 583
1990 538
1991 547
1992 494
1993 470
1994 362
1995 346
1996 304
1997 289
1998 265
1999 269
2000 260
2001 228
2002 228
2003 211
2004 209
2005 212
2006 184
2007 213
2008 179
2009 182
2010 157
2011 186
2012 198
2013 204
2014 179
2015 190
2016 152
2017 130
2018 127
2019 137
2020 136
2021 134
2022 116
2023 116
2024 133
2025 40

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25,018 results

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Page 1
A literature perspective on the pharmacological applications of yohimbine.
Jabir NR, Firoz CK, Zughaibi TA, Alsaadi MA, Abuzenadah AM, Al-Asmari AI, Alsaieedi A, Ahmed BA, Ramu AK, Tabrez S. Jabir NR, et al. Ann Med. 2022 Dec;54(1):2861-2875. doi: 10.1080/07853890.2022.2131330. Ann Med. 2022. PMID: 36263866 Free PMC article. Review.
The pharmacological activity of yohimbine is mediated by the combined action of the central and peripheral nervous systems. It selectively blocks the pre and postsynaptic alpha(2)-adrenergic receptors and has a moderate affinity for alpha1 and alpha2 subtypes. Yohimbine …
The pharmacological activity of yohimbine is mediated by the combined action of the central and peripheral nervous systems. It select …
Yohimbine as a pharmacological probe for alcohol research: a systematic review of rodent and human studies.
Curley DE, Vasaturo-Kolodner TR, Cannella N, Ciccocioppo R, Haass-Koffler CL. Curley DE, et al. Neuropsychopharmacology. 2022 Nov;47(12):2111-2122. doi: 10.1038/s41386-022-01363-9. Epub 2022 Jun 27. Neuropsychopharmacology. 2022. PMID: 35760866 Free PMC article.
Support for the use of yohimbine as a fully translational tool, however, is hindered by limited available findings from human laboratory studies, as well as a dearth of studies examining sex differences in yohimbine's mechanistic actions. Additional considera …
Support for the use of yohimbine as a fully translational tool, however, is hindered by limited available findings from human laborat …
Yohimbine.
Shannon M, Neuman MI. Shannon M, et al. Pediatr Emerg Care. 2000 Feb;16(1):49-50. doi: 10.1097/00006565-200002000-00015. Pediatr Emerg Care. 2000. PMID: 10698146 Review. No abstract available.
Yohimbine: a clinical review.
Tam SW, Worcel M, Wyllie M. Tam SW, et al. Pharmacol Ther. 2001 Sep;91(3):215-43. doi: 10.1016/s0163-7258(01)00156-5. Pharmacol Ther. 2001. PMID: 11744068 Review.
Although yohimbine (YOH) has been available for the treatment of male erectile dysfunction (ED) for longer than Viagra, there is a perception that little is known about the clinical performance of the drug. ...
Although yohimbine (YOH) has been available for the treatment of male erectile dysfunction (ED) for longer than Viagra, there is a pe …
Yohimbine in the treatment of erectile disorder.
Riley AJ. Riley AJ. Br J Clin Pract. 1994 May-Jun;48(3):133-6. Br J Clin Pract. 1994. PMID: 8031688 Review.
Yohimbine is an alkaloid derived mainly from the bark of the African tree, Pausinystalia yohimbe. ...Yohimbine has been evaluated in the management of erectile disorder by means of placebo-controlled but often poorly designed trials. ...
Yohimbine is an alkaloid derived mainly from the bark of the African tree, Pausinystalia yohimbe. ...Yohimbine has been evalua …
Multifaced Nature of Yohimbine-A Promising Therapeutic Potential or a Risk?
Nowacka A, Śniegocka M, Śniegocki M, Ziółkowska E, Bożiłow D, Smuczyński W. Nowacka A, et al. Int J Mol Sci. 2024 Nov 29;25(23):12856. doi: 10.3390/ijms252312856. Int J Mol Sci. 2024. PMID: 39684567 Free PMC article. Review.
Ongoing researches help to fully assess yohimbine's efficacy and safety profile and to explore strategies for enhancing its bioavailability and reducing toxicity. This review examines the multifaceted nature of yohimbine, delving into both its promising thera …
Ongoing researches help to fully assess yohimbine's efficacy and safety profile and to explore strategies for enhancing its bi …
Yohimbine in erectile dysfunction: would an orphan drug ever be properly assessed?
Morales A. Morales A. World J Urol. 2001 Aug;19(4):251-5. doi: 10.1007/s003450000182. World J Urol. 2001. PMID: 11550783 Review.
In-depth, systematic studies in animals have shown that yohimbine has a remarkable positive effect on sexual performance. Meta-analyses of the few controlled, randomized human studies have consistently shown an advantage of yohimbine over placebo. ...Another promisi …
In-depth, systematic studies in animals have shown that yohimbine has a remarkable positive effect on sexual performance. Meta-analys …
Yohimbine use for physical enhancement and its potential toxicity.
Cimolai N, Cimolai T. Cimolai N, et al. J Diet Suppl. 2011 Dec;8(4):346-54. doi: 10.3109/19390211.2011.615806. Epub 2011 Oct 21. J Diet Suppl. 2011. PMID: 22432773 Review.
Yohimbine is a naturally sourced pharmacological agent, which produces hyperadrenergic physiological effects. ...
Yohimbine is a naturally sourced pharmacological agent, which produces hyperadrenergic physiological effects. ...
Yohimbine in erectile dysfunction: the facts.
Morales A. Morales A. Int J Impot Res. 2000 Mar;12 Suppl 1:S70-74. Int J Impot Res. 2000. PMID: 10845767 Review.
In short, properly designed trials in humans have not been done. Why? Yohimbine is an old drug. As such it does not enjoy patent protection or commercial viability. Until molecular/formulation changes can be brought about (as recently happened with two other agents: phento …
In short, properly designed trials in humans have not been done. Why? Yohimbine is an old drug. As such it does not enjoy patent prot …
Yohimbine: time for resurrection?
[No authors listed] [No authors listed] Lancet. 1986 Nov 22;2(8517):1194-5. Lancet. 1986. PMID: 2877331 No abstract available.
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