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Son1p is a component of the 26S proteasome of the yeast Saccharomyces cerevisiae.
Fujimuro M, Tanaka K, Yokosawa H, Toh-e A. Fujimuro M, et al. Among authors: yokosawa h. FEBS Lett. 1998 Feb 20;423(2):149-54. doi: 10.1016/s0014-5793(98)00084-2. FEBS Lett. 1998. PMID: 9512348
Aaptamine, an alkaloid from the sponge Aaptos suberitoides, functions as a proteasome inhibitor.
Tsukamoto S, Yamanokuchi R, Yoshitomi M, Sato K, Ikeda T, Rotinsulu H, Mangindaan RE, de Voogd NJ, van Soest RW, Yokosawa H. Tsukamoto S, et al. Among authors: yokosawa h. Bioorg Med Chem Lett. 2010 Jun 1;20(11):3341-3. doi: 10.1016/j.bmcl.2010.04.029. Epub 2010 Apr 14. Bioorg Med Chem Lett. 2010. PMID: 20451377
Synthesis of 2,3- and 3,4-methanoamino acid equivalents with stereochemical diversity and their conversion into the tripeptide proteasome inhibitor belactosin a and its highly potent cis-cyclopropane stereoisomer.
Yoshida K, Yamaguchi K, Sone T, Unno Y, Asai A, Yokosawa H, Matsuda A, Arisawa M, Shuto S. Yoshida K, et al. Among authors: yokosawa h. Org Lett. 2008 Aug 21;10(16):3571-4. doi: 10.1021/ol8013304. Epub 2008 Jul 19. Org Lett. 2008. PMID: 18642830
ISG15 modification of Ubc13 suppresses its ubiquitin-conjugating activity.
Takeuchi T, Yokosawa H. Takeuchi T, et al. Among authors: yokosawa h. Biochem Biophys Res Commun. 2005 Oct 14;336(1):9-13. doi: 10.1016/j.bbrc.2005.08.034. Biochem Biophys Res Commun. 2005. PMID: 16112642
Siladenoserinols A-L: new sulfonated serinol derivatives from a tunicate as inhibitors of p53-Hdm2 interaction.
Nakamura Y, Kato H, Nishikawa T, Iwasaki N, Suwa Y, Rotinsulu H, Losung F, Maarisit W, Mangindaan RE, Morioka H, Yokosawa H, Tsukamoto S. Nakamura Y, et al. Among authors: yokosawa h. Org Lett. 2013 Jan 18;15(2):322-5. doi: 10.1021/ol3032363. Epub 2012 Dec 26. Org Lett. 2013. PMID: 23268733
Polyubiquitination of the B-cell translocation gene 1 and 2 proteins is promoted by the SCF ubiquitin ligase complex containing ╬▓TrCP.
Sasajima H, Nakagawa K, Kashiwayanagi M, Yokosawa H. Sasajima H, et al. Among authors: yokosawa h. Biol Pharm Bull. 2012;35(9):1539-45. doi: 10.1248/bpb.b12-00330. Biol Pharm Bull. 2012. PMID: 22975506
[A new mechanism of ubiquitin-dependent proteolytic pathway--polyubiquitin chain recognition and proteasomal targeting].
Kawahara H, Yokosawa H. Kawahara H, et al. Among authors: yokosawa h. Gan To Kagaku Ryoho. 2008 Jan;35(1):11-5. Gan To Kagaku Ryoho. 2008. PMID: 18195523 Japanese.
Intracellularly inducible, ubiquitin hydrolase-insensitive tandem ubiquitins inhibit the 26S proteasome activity and cell division.
Saeki Y, Isono E, Oguchi T, Shimada M, Sone T, Kawahara H, Yokosawa H, Toh-e A. Saeki Y, et al. Among authors: yokosawa h. Genes Genet Syst. 2004 Apr;79(2):77-86. doi: 10.1266/ggs.79.77. Genes Genet Syst. 2004. PMID: 15215673
New polyhydroxy sterols: proteasome inhibitors from a marine sponge Acanthodendrilla sp.
Tsukamoto S, Tatsuno M, van Soest RW, Yokosawa H, Ohta T. Tsukamoto S, et al. Among authors: yokosawa h. J Nat Prod. 2003 Sep;66(9):1181-5. doi: 10.1021/np030120v. J Nat Prod. 2003. PMID: 14510593
N-Terminal modifications of the 19S regulatory particle subunits of the yeast proteasome.
Kimura Y, Saeki Y, Yokosawa H, Polevoda B, Sherman F, Hirano H. Kimura Y, et al. Among authors: yokosawa h. Arch Biochem Biophys. 2003 Jan 15;409(2):341-8. doi: 10.1016/s0003-9861(02)00639-2. Arch Biochem Biophys. 2003. PMID: 12504901
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