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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 1
2005 3
2006 1
2007 4
2008 14
2009 22
2010 21
2011 18
2012 20
2013 29
2014 22
2015 23
2016 16
2017 15
2018 18
2019 16
2020 14
2021 16
2022 17
2023 12
2024 12

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272 results

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Page 1
Potential Application of Yokukansan as a Remedy for Parkinson's Disease.
Jang JH, Jung K, Kim JS, Jung I, Yoo H, Moon C. Jang JH, et al. Evid Based Complement Alternat Med. 2018 Dec 20;2018:1875928. doi: 10.1155/2018/1875928. eCollection 2018. Evid Based Complement Alternat Med. 2018. PMID: 30671124 Free PMC article. Review.
There have been efforts to develop complementary and alternative therapies for incurable PD. Yokukansan (YKS) is a traditional herbal medicine that is widely used for treating neurosis, insomnia, and night crying in children. ...
There have been efforts to develop complementary and alternative therapies for incurable PD. Yokukansan (YKS) is a traditional herbal …
Yokukansan in the treatment of behavioral and psychological symptoms of dementia: a systematic review and meta-analysis of randomized controlled trials.
Matsuda Y, Kishi T, Shibayama H, Iwata N. Matsuda Y, et al. Hum Psychopharmacol. 2013 Jan;28(1):80-6. doi: 10.1002/hup.2286. Hum Psychopharmacol. 2013. PMID: 23359469 Review.
Mini-mental state examination scores did not differ between the Yokukansan and UC treatment groups. Yokukansan was not different from UC regarding discontinuation due to any cause. CONCLUSION: Our results suggest that Yokukansan has a beneficial effect on NPI …
Mini-mental state examination scores did not differ between the Yokukansan and UC treatment groups. Yokukansan was not differe …
Yokukansan and its ingredients as possible treatment options for schizophrenia.
Yu CH, Ishii R, Yu SC, Takeda M. Yu CH, et al. Neuropsychiatr Dis Treat. 2014 Sep 1;10:1629-34. doi: 10.2147/NDT.S67607. eCollection 2014. Neuropsychiatr Dis Treat. 2014. PMID: 25210456 Free PMC article. Review.
As a result, searching for comparable treatment options with safer profiles is very important. Yokukansan (TJ-54), also called yi-gan san in Chinese, is a traditional herbal medicine with evident therapeutic effect for neuropsychiatric disorders. There …
As a result, searching for comparable treatment options with safer profiles is very important. Yokukansan (TJ-54), also called yi
Yokukansan enhances the proliferation of B65 neuroblastoma.
Nakatani Y, Amano T, Yamamoto H, Sakai N, Tsuji M, Takeda H. Nakatani Y, et al. J Tradit Complement Med. 2016 Feb 22;7(1):34-44. doi: 10.1016/j.jtcme.2016.01.006. eCollection 2017 Jan. J Tradit Complement Med. 2016. PMID: 28053886 Free PMC article.
Moreover, it has been shown that yokukansan has antidepressant-like and pain-relieving effects in animal models. ...We assessed the effect of yokukansan on p44/42 mitogen-activated protein kinase (MAPK) phosphorylation in B65 neuroblastoma cells, and found that y
Moreover, it has been shown that yokukansan has antidepressant-like and pain-relieving effects in animal models. ...We assessed the e …
Pharmacological Management of Lewy Body Dementia: A Systematic Review and Meta-Analysis.
Stinton C, McKeith I, Taylor JP, Lafortune L, Mioshi E, Mak E, Cambridge V, Mason J, Thomas A, O'Brien JT. Stinton C, et al. Am J Psychiatry. 2015 Aug 1;172(8):731-42. doi: 10.1176/appi.ajp.2015.14121582. Epub 2015 Jun 18. Am J Psychiatry. 2015. PMID: 26085043 Free article. Review.
Descriptive summaries provide some evidence of benefits for galantamine, modafinil, levodopa, rotigotine, clozapine, duloxetine, clonazepam, ramelteon, gabapentin, zonisamide, and yokukansan. Piracetam, amantadine, selegiline, olanzapine, quetiapine, risperidone, and cital …
Descriptive summaries provide some evidence of benefits for galantamine, modafinil, levodopa, rotigotine, clozapine, duloxetine, clonazepam, …
Yokukansan (TJ-54) in patients undergoing surgery: A systematic review and meta-analysis.
Kotake K, Matsunuma S, Takahashi T, Kitamura N, Kawakami Y. Kotake K, et al. Geriatr Nurs. 2023 Jul-Aug;52:8-15. doi: 10.1016/j.gerinurse.2023.04.014. Epub 2023 May 15. Geriatr Nurs. 2023. PMID: 37196515
OBJECTIVES: To evaluate the efficacy and safety of Yokukansan (TJ-54) in patients undergoing surgery. METHODS: Efficacy was assessed by the onset of delirium, delirium rating scales, anxiety evaluated by Hospital Anxiety and Depression Scale-Anxiety (HADS-A) score, and saf …
OBJECTIVES: To evaluate the efficacy and safety of Yokukansan (TJ-54) in patients undergoing surgery. METHODS: Efficacy was assessed …
Use of Yokukansan (TJ-54) in the treatment of neurological disorders: a review.
de Caires S, Steenkamp V. de Caires S, et al. Phytother Res. 2010 Sep;24(9):1265-70. doi: 10.1002/ptr.3146. Phytother Res. 2010. PMID: 20812276 Review.
Yokukansan is used to treat insomnia and irritability as well as screaming attacks, sleep tremors and hypnic myoclonia, and neurological disorders which include dementia and Alzheimer's disease - the focus of this article. It is concluded that Yokukansan is a versat
Yokukansan is used to treat insomnia and irritability as well as screaming attacks, sleep tremors and hypnic myoclonia, and neurologi
Yokukansan-induced reduction of ethanol preference is associated with antagonism of 5-HT3 receptors.
Nakamura Y, Kondo M, Koyama Y, Shimada S. Nakamura Y, et al. Phytomedicine. 2019 Jun;59:152897. doi: 10.1016/j.phymed.2019.152897. Epub 2019 Mar 20. Phytomedicine. 2019. PMID: 30974311
However, the effect of yokukansan on alcohol preference is not clear. PURPOSE: This study was performed to investigate the direct effect of yokukansan on alcohol preference and the effect of 5-HT(3) receptors on the preference. STUDY DESIGN: We examined ethanol pref …
However, the effect of yokukansan on alcohol preference is not clear. PURPOSE: This study was performed to investigate the direct eff …
Cellular Pharmacological Effects of the Traditional Japanese Kampo Medicine Yokukansan on Brain Cells.
Mizoguchi K, Ikarashi Y. Mizoguchi K, et al. Front Pharmacol. 2017 Sep 20;8:655. doi: 10.3389/fphar.2017.00655. eCollection 2017. Front Pharmacol. 2017. PMID: 28979206 Free PMC article. Review.
Yokukansan (YKS) is a traditional Japanese Kampo medicine currently used for the treatment of the behavioral psychological symptoms associated with dementia (BPSD), which is frequently problematic in neurodegenerative disorders such as Alzheimer's disease. ...
Yokukansan (YKS) is a traditional Japanese Kampo medicine currently used for the treatment of the behavioral psychological symptoms a
272 results