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Capsinoids and related food ingredients activating brown fat thermogenesis and reducing body fat in humans.
Saito M, Yoneshiro T. Saito M, et al. Among authors: yoneshiro t. Curr Opin Lipidol. 2013 Feb;24(1):71-7. doi: 10.1097/MOL.0b013e32835a4f40. Curr Opin Lipidol. 2013. PMID: 23298960 Review.
High incidence of metabolically active brown adipose tissue in healthy adult humans: effects of cold exposure and adiposity.
Saito M, Okamatsu-Ogura Y, Matsushita M, Watanabe K, Yoneshiro T, Nio-Kobayashi J, Iwanaga T, Miyagawa M, Kameya T, Nakada K, Kawai Y, Tsujisaki M. Saito M, et al. Among authors: yoneshiro t. Diabetes. 2009 Jul;58(7):1526-31. doi: 10.2337/db09-0530. Epub 2009 Apr 28. Diabetes. 2009. PMID: 19401428 Free PMC article.
Brown adipose tissue, whole-body energy expenditure, and thermogenesis in healthy adult men.
Yoneshiro T, Aita S, Matsushita M, Kameya T, Nakada K, Kawai Y, Saito M. Yoneshiro T, et al. Obesity (Silver Spring). 2011 Jan;19(1):13-6. doi: 10.1038/oby.2010.105. Epub 2010 May 6. Obesity (Silver Spring). 2011. PMID: 20448535 Clinical Trial.
Age-related decrease in cold-activated brown adipose tissue and accumulation of body fat in healthy humans.
Yoneshiro T, Aita S, Matsushita M, Okamatsu-Ogura Y, Kameya T, Kawai Y, Miyagawa M, Tsujisaki M, Saito M. Yoneshiro T, et al. Obesity (Silver Spring). 2011 Sep;19(9):1755-60. doi: 10.1038/oby.2011.125. Epub 2011 May 12. Obesity (Silver Spring). 2011. PMID: 21566561
Nonpungent capsaicin analogs (capsinoids) increase energy expenditure through the activation of brown adipose tissue in humans.
Yoneshiro T, Aita S, Kawai Y, Iwanaga T, Saito M. Yoneshiro T, et al. Am J Clin Nutr. 2012 Apr;95(4):845-50. doi: 10.3945/ajcn.111.018606. Epub 2012 Feb 29. Am J Clin Nutr. 2012. PMID: 22378725 Clinical Trial.
Impact of UCP1 and β3AR gene polymorphisms on age-related changes in brown adipose tissue and adiposity in humans.
Yoneshiro T, Ogawa T, Okamoto N, Matsushita M, Aita S, Kameya T, Kawai Y, Iwanaga T, Saito M. Yoneshiro T, et al. Int J Obes (Lond). 2013 Jul;37(7):993-8. doi: 10.1038/ijo.2012.161. Epub 2012 Oct 2. Int J Obes (Lond). 2013. PMID: 23032405
Grains of paradise (Aframomum melegueta) extract activates brown adipose tissue and increases whole-body energy expenditure in men.
Sugita J, Yoneshiro T, Hatano T, Aita S, Ikemoto T, Uchiwa H, Iwanaga T, Kameya T, Kawai Y, Saito M. Sugita J, et al. Among authors: yoneshiro t. Br J Nutr. 2013 Aug;110(4):733-8. doi: 10.1017/S0007114512005715. Epub 2013 Jan 11. Br J Nutr. 2013. PMID: 23308394 Clinical Trial.
Recruited brown adipose tissue as an antiobesity agent in humans.
Yoneshiro T, Aita S, Matsushita M, Kayahara T, Kameya T, Kawai Y, Iwanaga T, Saito M. Yoneshiro T, et al. J Clin Invest. 2013 Aug;123(8):3404-8. doi: 10.1172/JCI67803. Epub 2013 Jul 15. J Clin Invest. 2013. PMID: 23867622 Free PMC article. Clinical Trial.
Transient receptor potential activated brown fat thermogenesis as a target of food ingredients for obesity management.
Yoneshiro T, Saito M. Yoneshiro T, et al. Curr Opin Clin Nutr Metab Care. 2013 Nov;16(6):625-31. doi: 10.1097/MCO.0b013e3283653ee1. Curr Opin Clin Nutr Metab Care. 2013. PMID: 24100669 Review.
Impact of brown adipose tissue on body fatness and glucose metabolism in healthy humans.
Matsushita M, Yoneshiro T, Aita S, Kameya T, Sugie H, Saito M. Matsushita M, et al. Among authors: yoneshiro t. Int J Obes (Lond). 2014 Jun;38(6):812-7. doi: 10.1038/ijo.2013.206. Epub 2013 Nov 11. Int J Obes (Lond). 2014. PMID: 24213309
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