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Antibiotic administration can eradicate intra-amniotic infection or intra-amniotic inflammation in a subset of patients with preterm labor and intact membranes.
Yoon BH, Romero R, Park JY, Oh KJ, Lee J, Conde-Agudelo A, Hong JS. Yoon BH, et al. Am J Obstet Gynecol. 2019 Aug;221(2):142.e1-142.e22. doi: 10.1016/j.ajog.2019.03.018. Epub 2019 Mar 27. Am J Obstet Gynecol. 2019. PMID: 30928566
Evidence that antibiotic administration is effective in the treatment of a subset of patients with intra-amniotic infection/inflammation presenting with cervical insufficiency.
Oh KJ, Romero R, Park JY, Lee J, Conde-Agudelo A, Hong JS, Yoon BH. Oh KJ, et al. Am J Obstet Gynecol. 2019 Aug;221(2):140.e1-140.e18. doi: 10.1016/j.ajog.2019.03.017. Epub 2019 Mar 28. Am J Obstet Gynecol. 2019. PMID: 30928565 Free PMC article.
Twenty-four percent of patients with clinical chorioamnionitis in preterm gestations have no evidence of either culture-proven intraamniotic infection or intraamniotic inflammation.
Oh KJ, Kim SM, Hong JS, Maymon E, Erez O, Panaitescu B, Gomez-Lopez N, Romero R, Yoon BH. Oh KJ, et al. Am J Obstet Gynecol. 2017 Jun;216(6):604.e1-604.e11. doi: 10.1016/j.ajog.2017.02.035. Epub 2017 Feb 28. Am J Obstet Gynecol. 2017. PMID: 28257964 Free PMC article.
Prevalence and clinical significance of sterile intra-amniotic inflammation in patients with preterm labor and intact membranes.
Romero R, Miranda J, Chaiworapongsa T, Korzeniewski SJ, Chaemsaithong P, Gotsch F, Dong Z, Ahmed AI, Yoon BH, Hassan SS, Kim CJ, Yeo L. Romero R, et al. Am J Reprod Immunol. 2014 Nov;72(5):458-74. doi: 10.1111/aji.12296. Epub 2014 Jul 31. Am J Reprod Immunol. 2014. PMID: 25078709 Free PMC article.
Which is more important for the intensity of intra-amniotic inflammation between total grade or involved anatomical region in preterm gestations with acute histologic chorioamnionitis?
Park CW, Yoon BH, Kim SM, Park JS, Jun JK. Park CW, et al. Obstet Gynecol Sci. 2013 Jul;56(4):227-33. doi: 10.5468/ogs.2013.56.4.227. Epub 2013 Jul 15. Obstet Gynecol Sci. 2013. PMID: 24328007 Free PMC article.
Intraamniotic infection with genital mycoplasmas exhibits a more intense inflammatory response than intraamniotic infection with other microorganisms in patients with preterm premature rupture of membranes.
Oh KJ, Lee KA, Sohn YK, Park CW, Hong JS, Romero R, Yoon BH. Oh KJ, et al. Am J Obstet Gynecol. 2010 Sep;203(3):211.e1-8. doi: 10.1016/j.ajog.2010.03.035. Epub 2010 Aug 3. Am J Obstet Gynecol. 2010. PMID: 20678747 Free PMC article.
The frequency of microbial invasion of the amniotic cavity and histologic chorioamnionitis in women at term with intact membranes in the presence or absence of labor.
Seong HS, Lee SE, Kang JH, Romero R, Yoon BH. Seong HS, et al. Am J Obstet Gynecol. 2008 Oct;199(4):375.e1-5. doi: 10.1016/j.ajog.2008.06.040. Am J Obstet Gynecol. 2008. PMID: 18928978 Free PMC article.
The intensity of the fetal inflammatory response in intraamniotic inflammation with and without microbial invasion of the amniotic cavity.
Lee SE, Romero R, Jung H, Park CW, Park JS, Yoon BH. Lee SE, et al. Am J Obstet Gynecol. 2007 Sep;197(3):294.e1-6. doi: 10.1016/j.ajog.2007.07.006. Am J Obstet Gynecol. 2007. PMID: 17826426
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