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Two-sided roles of IL-27: induction of Th1 differentiation on naive CD4+ T cells versus suppression of proinflammatory cytokine production including IL-23-induced IL-17 on activated CD4+ T cells partially through STAT3-dependent mechanism.
Yoshimura T, Takeda A, Hamano S, Miyazaki Y, Kinjyo I, Ishibashi T, Yoshimura A, Yoshida H. Yoshimura T, et al. Among authors: yoshida h. J Immunol. 2006 Oct 15;177(8):5377-85. doi: 10.4049/jimmunol.177.8.5377. J Immunol. 2006. PMID: 17015723
SOCS1/JAB is a negative regulator of LPS-induced macrophage activation.
Kinjyo I, Hanada T, Inagaki-Ohara K, Mori H, Aki D, Ohishi M, Yoshida H, Kubo M, Yoshimura A. Kinjyo I, et al. Among authors: yoshida h. Immunity. 2002 Nov;17(5):583-91. doi: 10.1016/s1074-7613(02)00446-6. Immunity. 2002. PMID: 12433365 Free article.
7,821 results