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Role of the 8-double bond of lanosterol in the enzyme-substrate interaction of cytochrome P-450(14DM) (lanosterol 14 alpha-demethylase).
Aoyama Y, Yoshida Y, Sonoda Y, Sato Y. Aoyama Y, et al. Among authors: yoshida y. Biochim Biophys Acta. 1989 Feb 6;1001(2):196-200. Biochim Biophys Acta. 1989. PMID: 2917143
Oxidative metabolism of 5-methoxy-N,N-diisopropyltryptamine (Foxy) by human liver microsomes and recombinant cytochrome P450 enzymes.
Narimatsu S, Yonemoto R, Saito K, Takaya K, Kumamoto T, Ishikawa T, Asanuma M, Funada M, Kiryu K, Naito S, Yoshida Y, Yamamoto S, Hanioka N. Narimatsu S, et al. Among authors: yoshida y. Biochem Pharmacol. 2006 Apr 28;71(9):1377-85. doi: 10.1016/j.bcp.2006.01.015. Epub 2006 Feb 28. Biochem Pharmacol. 2006. PMID: 16510126
Characterization of moss ent-kaurene oxidase (CYP701B1) using a highly purified preparation.
Noguchi C, Miyazaki S, Kawaide H, Gotoh O, Yoshida Y, Aoyama Y. Noguchi C, et al. Among authors: yoshida y. J Biochem. 2018 Jan 1;163(1):69-76. doi: 10.1093/jb/mvx063. J Biochem. 2018. PMID: 29036583
The 50th anniversary and new horizons of cytochrome P450 research: expanding knowledge on the multiplicity and versatility of P450 and its industrial applications. Foreword.
Yoshida Y. Yoshida Y. Biol Pharm Bull. 2012;35(6):811. doi: 10.1248/bpb.35.811. Biol Pharm Bull. 2012. PMID: 22687467 No abstract available.
[Meaning of molecular and functional multiplicity of P450 monooxygenase as the bio-defense system against xenobiotics].
Yoshida Y. Yoshida Y. Seikagaku. 2003 Mar;75(3):195-203. Seikagaku. 2003. PMID: 12704840 Review. Japanese. No abstract available.
Studies on the expression levels of sterol-metabolizing enzymes in the obese model SHR/NDmcr-cp rats.
Kudo M, Noshiro M, Aoyama Y, Yoshida Y. Kudo M, et al. Among authors: yoshida y. Clin Exp Pharmacol Physiol. 2004 Dec;31 Suppl 2:S57-9. doi: 10.1111/j.1440-1681.2004.04107.x. Clin Exp Pharmacol Physiol. 2004. PMID: 15649292
Structure-based de novo design, synthesis, and biological evaluation of non-azole inhibitors specific for lanosterol 14alpha-demethylase of fungi.
Ji H, Zhang W, Zhang M, Kudo M, Aoyama Y, Yoshida Y, Sheng C, Song Y, Yang S, Zhou Y, Lü J, Zhu J. Ji H, et al. Among authors: yoshida y. J Med Chem. 2003 Feb 13;46(4):474-85. doi: 10.1021/jm020362c. J Med Chem. 2003. PMID: 12570370
Effects of Y132H and F145L substitutions on the activity, azole resistance and spectral properties of Candida albicans sterol 14-demethylase P450 (CYP51): a live example showing the selection of altered P450 through interaction with environmental compounds.
Kudo M, Ohi M, Aoyama Y, Nitahara Y, Chung SK, Yoshida Y. Kudo M, et al. Among authors: yoshida y. J Biochem. 2005 May;137(5):625-32. doi: 10.1093/jb/mvi073. J Biochem. 2005. PMID: 15944416
The construction and characterization of self-sufficient lanosterol 14-demethylase fusion proteins consisting of yeast CYP51 and its reductase.
Kitahama Y, Nakamura M, Yoshida Y, Aoyama Y. Kitahama Y, et al. Among authors: yoshida y. Biol Pharm Bull. 2009 Apr;32(4):558-63. doi: 10.1248/bpb.32.558. Biol Pharm Bull. 2009. PMID: 19336884
β-Amyrin oxidation by oat CYP51H10 expressed heterologously in yeast cells: the first example of CYP51-dependent metabolism other than the 14-demethylation of sterol precursors.
Kunii M, Kitahama Y, Fukushima EO, Seki H, Muranaka T, Yoshida Y, Aoyama Y. Kunii M, et al. Among authors: yoshida y. Biol Pharm Bull. 2012;35(5):801-4. doi: 10.1248/bpb.35.801. Biol Pharm Bull. 2012. PMID: 22687421
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