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Ca v 1.2 L-type Ca2+ channel protects mast cells against activation-induced cell death by preventing mitochondrial integrity disruption.
Suzuki Y, Yoshimaru T, Inoue T, Ra C. Suzuki Y, et al. Among authors: yoshimaru t. Mol Immunol. 2009 Jul;46(11-12):2370-80. doi: 10.1016/j.molimm.2009.03.017. Epub 2009 May 17. Mol Immunol. 2009. PMID: 19447492
Recently, store-independent Ca(2+) channels which are pharmacologically and/or immunologically similar to L-type Ca(2+) channels (LTCCs) have been shown to exist in various hematopoietic cells, including T cells, B cells and neutrophils. ...
Recently, store-independent Ca(2+) channels which are pharmacologically and/or immunologically similar to L-type Ca(2+) channels (LTCCs) hav …
FcepsilonRI beta-chain ITAM amplifies PI3K-signaling to ensure synergistic degranulation response via FcepsilonRI and adenosine receptors.
Nunomura S, Gon Y, Yoshimaru T, Kashiwakura J, Kawakami T, Ra C. Nunomura S, et al. Among authors: yoshimaru t. Eur J Immunol. 2010 Apr;40(4):1205-17. doi: 10.1002/eji.200939651. Eur J Immunol. 2010. PMID: 20101614
SHP-1 exhibits a pro-apoptotic function in antigen-stimulated mast cells: positive regulation of mitochondrial death pathways and negative regulation of survival signaling pathways.
Inoue T, Suzuki Y, Mizuno K, Nakata K, Yoshimaru T, Ra C. Inoue T, et al. Among authors: yoshimaru t. Mol Immunol. 2009 Dec;47(2-3):222-32. doi: 10.1016/j.molimm.2009.09.033. Epub 2009 Oct 28. Mol Immunol. 2009. PMID: 19875169
Nitric Oxide positively regulates Ag (I)-induced Ca(2+) influx and mast cell activation: role of a Nitric Oxide Synthase-independent pathway.
Inoue T, Suzuki Y, Yoshimaru T, Ra C. Inoue T, et al. Among authors: yoshimaru t. J Leukoc Biol. 2009 Dec;86(6):1365-75. doi: 10.1189/jlb.0609387. Epub 2009 Aug 25. J Leukoc Biol. 2009. PMID: 19706839
Discrete generations of intracellular hydrogen peroxide and superoxide in antigen-stimulated mast cells: reciprocal regulation of store-operated Ca2+ channel activity.
Suzuki Y, Yoshimaru T, Inoue T, Ra C. Suzuki Y, et al. Among authors: yoshimaru t. Mol Immunol. 2009 Jul;46(11-12):2200-9. doi: 10.1016/j.molimm.2009.04.013. Epub 2009 May 20. Mol Immunol. 2009. PMID: 19467708
Mast cells and T cells produce reactive oxygen species (ROS) after stimulation with the high-affinity IgE receptor (Fc epsilon RI) and T cell receptor. ...
Mast cells and T cells produce reactive oxygen species (ROS) after stimulation with the high-affinity IgE receptor (Fc epsilon RI) an …
Ca2+-dependent mast cell death induced by Ag (I) via cardiolipin oxidation and ATP depletion.
Inoue T, Suzuki Y, Yoshimaru T, Ra C. Inoue T, et al. Among authors: yoshimaru t. J Leukoc Biol. 2009 Jul;86(1):167-79. doi: 10.1189/jlb.1108691. Epub 2009 Apr 28. J Leukoc Biol. 2009. PMID: 19401388
Aspirin and salicylates modulate IgE-mediated leukotriene secretion in mast cells through a dihydropyridine receptor-mediated Ca(2+) influx.
Togo K, Suzuki Y, Yoshimaru T, Inoue T, Terui T, Ochiai T, Ra C. Togo K, et al. Among authors: yoshimaru t. Clin Immunol. 2009 Apr;131(1):145-56. doi: 10.1016/j.clim.2008.09.008. Epub 2009 Jan 14. Clin Immunol. 2009. PMID: 19144570
L-type Ca2+ channels in mast cells: activation by membrane depolarization and distinct roles in regulating mediator release from store-operated Ca2+ channels.
Yoshimaru T, Suzuki Y, Inoue T, Ra C. Yoshimaru T, et al. Mol Immunol. 2009 Apr;46(7):1267-77. doi: 10.1016/j.molimm.2008.11.011. Epub 2009 Jan 6. Mol Immunol. 2009. PMID: 19128833
Positive and negative regulation of high affinity IgE receptor signaling by Src homology region 2 domain-containing phosphatase 1.
Nakata K, Yoshimaru T, Suzuki Y, Inoue T, Ra C, Yakura H, Mizuno K. Nakata K, et al. Among authors: yoshimaru t. J Immunol. 2008 Oct 15;181(8):5414-24. doi: 10.4049/jimmunol.181.8.5414. J Immunol. 2008. PMID: 18832698
Upon Fc epsilonRI ligation, motheaten-derived bone marrow-derived mast cells showed enhanced tyrosine phosphorylation of Src homology region 2 domain-containing leukocyte protein of 76 kDa (SLP-76) and linker for activation of T cells, activation of mitogen-activated prote …
Upon Fc epsilonRI ligation, motheaten-derived bone marrow-derived mast cells showed enhanced tyrosine phosphorylation of Src homology region …
Extracellular superoxide released from mitochondria mediates mast cell death by advanced glycation end products.
Yoshimaru T, Suzuki Y, Inoue T, Nishida S, Ra C. Yoshimaru T, et al. Biochim Biophys Acta. 2008 Dec;1783(12):2332-43. doi: 10.1016/j.bbamcr.2008.08.010. Epub 2008 Sep 6. Biochim Biophys Acta. 2008. PMID: 18822320
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