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Alpha cell dysfunction in type 1 diabetes.
Yosten GLC. Yosten GLC. Peptides. 2018 Feb;100:54-60. doi: 10.1016/j.peptides.2017.12.001. Peptides. 2018. PMID: 29412832 Review.
The melanocortins, not oxytocin, mediate the anorexigenic and antidipsogenic effects of neuronostatin.
Yosten GL, Samson WK. Yosten GL, et al. Peptides. 2010 Sep;31(9):1711-4. doi: 10.1016/j.peptides.2010.06.017. Epub 2010 Jun 25. Peptides. 2010. PMID: 20600426 Free PMC article.
Pressor doses of vasopressin result in only transient elevations in plasma peptide levels.
Yosten GL, Samson WK. Yosten GL, et al. Peptides. 2012 Feb;33(2):342-5. doi: 10.1016/j.peptides.2011.12.013. Epub 2011 Dec 31. Peptides. 2012. PMID: 22227112 Free PMC article.
Evidence for an interaction of neuronostatin with the orphan G protein-coupled receptor, GPR107.
Yosten GL, Redlinger LJ, Samson WK. Yosten GL, et al. Am J Physiol Regul Integr Comp Physiol. 2012 Nov 1;303(9):R941-9. doi: 10.1152/ajpregu.00336.2012. Epub 2012 Aug 29. Am J Physiol Regul Integr Comp Physiol. 2012. PMID: 22933024 Free PMC article.
Neuronostatin inhibits glucose-stimulated insulin secretion via direct action on the pancreatic α-cell.
Salvatori AS, Elrick MM, Samson WK, Corbett JA, Yosten GL. Salvatori AS, et al. Am J Physiol Endocrinol Metab. 2014 Jun 1;306(11):E1257-63. doi: 10.1152/ajpendo.00599.2013. Epub 2014 Apr 15. Am J Physiol Endocrinol Metab. 2014. PMID: 24735892 Free PMC article.
Low O2-induced ATP release from erythrocytes of humans with type 2 diabetes is restored by physiological ratios of C-peptide and insulin.
Richards JP, Yosten GL, Kolar GR, Jones CW, Stephenson AH, Ellsworth ML, Sprague RS. Richards JP, et al. Am J Physiol Regul Integr Comp Physiol. 2014 Oct 1;307(7):R862-8. doi: 10.1152/ajpregu.00206.2014. Epub 2014 Jul 30. Am J Physiol Regul Integr Comp Physiol. 2014. PMID: 25080497
Physiological effects and therapeutic potential of proinsulin C-peptide.
Yosten GL, Maric-Bilkan C, Luppi P, Wahren J. Yosten GL, et al. Am J Physiol Endocrinol Metab. 2014 Dec 1;307(11):E955-68. doi: 10.1152/ajpendo.00130.2014. Epub 2014 Sep 23. Am J Physiol Endocrinol Metab. 2014. PMID: 25249503 Free PMC article. Review.
Understanding peptide biology: The discovery and characterization of the novel hormone, neuronostatin.
Yosten GL, Elrick MM, Salvatori A, Stein LM, Kolar GR, Ren J, Corbett JA, Samson WK. Yosten GL, et al. Peptides. 2015 Oct;72:192-5. doi: 10.1016/j.peptides.2015.05.011. Epub 2015 Jun 4. Peptides. 2015. PMID: 26051024 Free PMC article. Review.
The Physiology of Proinsulin C-Peptide: Unanswered Questions and a Proposed Model.
Yosten GL, Kolar GR. Yosten GL, et al. Physiology (Bethesda). 2015 Jul;30(4):327-32. doi: 10.1152/physiol.00008.2015. Physiology (Bethesda). 2015. PMID: 26136546 Review.
Neuronostatin acts via GPR107 to increase cAMP-independent PKA phosphorylation and proglucagon mRNA accumulation in pancreatic α-cells.
Elrick MM, Samson WK, Corbett JA, Salvatori AS, Stein LM, Kolar GR, Naatz A, Yosten GL. Elrick MM, et al. Am J Physiol Regul Integr Comp Physiol. 2016 Jan 15;310(2):R143-55. doi: 10.1152/ajpregu.00369.2014. Epub 2015 Nov 11. Am J Physiol Regul Integr Comp Physiol. 2016. PMID: 26561648 Free PMC article.
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