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Inhibition of colony stimulating factor 1 receptor corrects maternal inflammation-induced microglial and synaptic dysfunction and behavioral abnormalities.
Ikezu S, Yeh H, Delpech JC, Woodbury ME, Van Enoo AA, Ruan Z, Sivakumaran S, You Y, Holland C, Guillamon-Vivancos T, Yoshii-Kitahara A, Botros MB, Madore C, Chao PH, Desani A, Manimaran S, Kalavai SV, Johnson WE, Butovsky O, Medalla M, Luebke JI, Ikezu T. Ikezu S, et al. Among authors: you y. Mol Psychiatry. 2021 Jun;26(6):1808-1831. doi: 10.1038/s41380-020-0671-2. Epub 2020 Feb 18. Mol Psychiatry. 2021. PMID: 32071385 Free PMC article.
Proteomic and biological profiling of extracellular vesicles from Alzheimer's disease human brain tissues.
Muraoka S, DeLeo AM, Sethi MK, Yukawa-Takamatsu K, Yang Z, Ko J, Hogan JD, Ruan Z, You Y, Wang Y, Medalla M, Ikezu S, Chen M, Xia W, Gorantla S, Gendelman HE, Issadore D, Zaia J, Ikezu T. Muraoka S, et al. Among authors: you y. Alzheimers Dement. 2020 Jun;16(6):896-907. doi: 10.1002/alz.12089. Epub 2020 Apr 17. Alzheimers Dement. 2020. PMID: 32301581 Free PMC article.
Protein phosphatase 2A and complement component 4 are linked to the protective effect of APOE ɛ2 for Alzheimer's disease.
Jun GR, You Y, Zhu C, Meng G, Chung J, Panitch R, Hu J, Xia W; Alzheimer's Disease Genetics Consortium; Bennett DA, Foroud TM, Wang LS, Haines JL, Mayeux R, Pericak-Vance MA, Schellenberg GD, Au R, Lunetta KL, Ikezu T, Stein TD, Farrer LA. Jun GR, et al. Among authors: you y. Alzheimers Dement. 2022 Nov;18(11):2042-2054. doi: 10.1002/alz.12607. Epub 2022 Feb 9. Alzheimers Dement. 2022. PMID: 35142023 Free PMC article.
Modeling Lewy body disease with SNCA triplication iPSC-derived cortical organoids and identifying therapeutic drugs.
Jin Y, Li F, Li Z, Ikezu TC, O'Leary J, Selvaraj M, Zhu Y, Martens YA, Koga S, Santhakumar H, Li Y, Lu W, You Y, Lolo K, DeTure M, Beasley AI, Davis MD, McLean PJ, Ross OA, Kanekiyo T, Ikezu T, Caulfield T, Carr J, Wszolek ZK, Bu G, Dickson DW, Zhao N. Jin Y, et al. Among authors: you y. Sci Adv. 2024 Sep 13;10(37):eadk3700. doi: 10.1126/sciadv.adk3700. Epub 2024 Sep 11. Sci Adv. 2024. PMID: 39259788 Free PMC article.
6,284 results