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PINK1 is degraded through the N-end rule pathway.
Yamano K, Youle RJ. Yamano K, et al. Among authors: youle rj. Autophagy. 2013 Nov 1;9(11):1758-69. doi: 10.4161/auto.24633. Epub 2013 Apr 17. Autophagy. 2013. PMID: 24121706 Free PMC article.
Mitochondrial fission in apoptosis.
Youle RJ, Karbowski M. Youle RJ, et al. Nat Rev Mol Cell Biol. 2005 Aug;6(8):657-63. doi: 10.1038/nrm1697. Nat Rev Mol Cell Biol. 2005. PMID: 16025099 Review.
Active state of Parkin.
Le Guerroué F, Youle RJ. Le Guerroué F, et al. Among authors: youle rj. Nat Struct Mol Biol. 2018 Aug;25(8):644-646. doi: 10.1038/s41594-018-0101-1. Nat Struct Mol Biol. 2018. PMID: 30038392 No abstract available.
Parkin and PINK1 mitigate STING-induced inflammation.
Sliter DA, Martinez J, Hao L, Chen X, Sun N, Fischer TD, Burman JL, Li Y, Zhang Z, Narendra DP, Cai H, Borsche M, Klein C, Youle RJ. Sliter DA, et al. Among authors: youle rj. Nature. 2018 Sep;561(7722):258-262. doi: 10.1038/s41586-018-0448-9. Epub 2018 Aug 22. Nature. 2018. PMID: 30135585 Free PMC article.
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