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Age-associated increase in rat ventricular ANP gene expression correlates with cardiac hypertrophy.
Younes A, Boluyt MO, O'Neill L, Meredith AL, Crow MT, Lakatta EG. Younes A, et al. Am J Physiol. 1995 Sep;269(3 Pt 2):H1003-8. doi: 10.1152/ajpheart.1995.269.3.H1003. Am J Physiol. 1995. PMID: 7573495
Ischemic preconditioning increases the bioavailability of cardiac enkephalins.
Younès A, Pepe S, Yoshishige D, Caffrey JL, Lakatta EG. Younès A, et al. Am J Physiol Heart Circ Physiol. 2005 Oct;289(4):H1652-61. doi: 10.1152/ajpheart.01110.2004. Am J Physiol Heart Circ Physiol. 2005. PMID: 16162869
Rapamycin inhibits alpha 1-adrenergic receptor-stimulated cardiac myocyte hypertrophy but not activation of hypertrophy-associated genes. Evidence for involvement of p70 S6 kinase.
Boluyt MO, Zheng JS, Younes A, Long X, O'Neill L, Silverman H, Lakatta EG, Crow MT. Boluyt MO, et al. Among authors: younes a. Circ Res. 1997 Aug;81(2):176-86. doi: 10.1161/01.res.81.2.176. Circ Res. 1997. PMID: 9242178
Age-associated increase in rat cardiac opioid production.
Boluyt MO, Younes A, Caffrey JL, O'Neill L, Barron BA, Crow MT, Lakatta EG. Boluyt MO, et al. Among authors: younes a. Am J Physiol. 1993 Jul;265(1 Pt 2):H212-8. doi: 10.1152/ajpheart.1993.265.1.H212. Am J Physiol. 1993. PMID: 8342635
Aging, cardiac proenkephalin mRNA and enkephalin peptides in the Fisher 344 rat.
Caffrey JL, Boluyt MO, Younes A, Barron BA, O'Neill L, Crow MT, Lakatta EG. Caffrey JL, et al. Among authors: younes a. J Mol Cell Cardiol. 1994 Jun;26(6):701-11. doi: 10.1006/jmcc.1994.1085. J Mol Cell Cardiol. 1994. PMID: 8089851
Impairments in both p70 S6 kinase and extracellular signal-regulated kinase signaling pathways contribute to the decline in proliferative capacity of aged hepatocytes.
Liu Y, Gorospe M, Kokkonen GC, Boluyt MO, Younes A, Mock YD, Wang X, Roth GS, Holbrook NJ. Liu Y, et al. Among authors: younes a. Exp Cell Res. 1998 Apr 10;240(1):40-8. doi: 10.1006/excr.1997.3931. Exp Cell Res. 1998. PMID: 9570919
Ca(2+) -stimulated basal adenylyl cyclase activity localization in membrane lipid microdomains of cardiac sinoatrial nodal pacemaker cells.
Younes A, Lyashkov AE, Graham D, Sheydina A, Volkova MV, Mitsak M, Vinogradova TM, Lukyanenko YO, Li Y, Ruknudin AM, Boheler KR, van Eyk J, Lakatta EG. Younes A, et al. J Biol Chem. 2008 May 23;283(21):14461-8. doi: 10.1074/jbc.M707540200. Epub 2008 Mar 20. J Biol Chem. 2008. PMID: 18356168 Free PMC article.
Activation of distinct cAMP-dependent and cGMP-dependent pathways by nitric oxide in cardiac myocytes.
Vila-Petroff MG, Younes A, Egan J, Lakatta EG, Sollott SJ. Vila-Petroff MG, et al. Among authors: younes a. Circ Res. 1999 May 14;84(9):1020-31. doi: 10.1161/01.res.84.9.1020. Circ Res. 1999. PMID: 10325239
Cardiac synthesis, processing, and coronary release of enkephalin-related peptides.
Younès A, Pepe S, Barron BA, Spurgeon HA, Lakatta EG, Caffrey JL. Younès A, et al. Am J Physiol Heart Circ Physiol. 2000 Oct;279(4):H1989-98. doi: 10.1152/ajpheart.2000.279.4.H1989. Am J Physiol Heart Circ Physiol. 2000. PMID: 11009489
Effects of ischemia on the metabolism of cardiac enkephalins.
Semmoum Y, Younes A, Coudert J. Semmoum Y, et al. Among authors: younes a. Arch Physiol Biochem. 2001 Feb;109(1):18-23. doi: 10.1076/apab. Arch Physiol Biochem. 2001. PMID: 11471067
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